A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes by Scott A. Salger (3072093)

“…The Class II piscidins (44–46 amino acids in length; striped bass and white bass piscidin 4 and white bass piscidin 5) have a level of activity against bacteria and protozoans intermediate to Classes I and III. …”

Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease by Gonçalo da Costa (198731)

“…Since non-mutated transthyretin also forms amyloid in systemic senile amyloidosis and some mutation bearers are asymptomatic throughout their lives, non-genetic factors must also be involved in transthyretin amyloidosis. We discovered, using a differential proteomics approach, that extracellular chaperones such as fibrinogen, clusterin, haptoglobin, alpha-1-anti-trypsin and 2-macroglobulin are overrepresented in transthyretin amyloidosis. …”

Does the presence of exotic species decrease the initial development of native species in Brazilian seasonally dry tropical forests? by Carlos Leandro Costa Silva (12741450)

SDG decreases iron-induced oxidative stress in H9c2 cells. by Stephanie Puukila (568109)

Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner by Qian Zhao (217607)

“…Results: For both WT and TLR9 KO mice, CpG significantly induced B cell proliferation, increased IL-10 mRNA expression and protein secretion of IL-10 but reduced CD1dhiCD5+ B cells population; local injection of CpG+CD40L mixture significantly decreased alveolar bone loss and the number of TRAP-positive cells adjacent to the alveolar bone surface, and significantly increased the gingival mRNA expression of IL-10 and decreased RANKL and IFN-γ mRNA expression. …”

We define the term “inhibitory reduction prowess” (IRP) as the percentage by which the product formation rate is reduced by from the initial point before inhibitor is introduced to... by J. Roadnight Sheehan (20141887)

Inhibition of PKC or Rho protein kinase decreases Ad5 wild type replication <i>in vitro</i>. by Alice Liu (4814415)

Primary cilia frequency is decreased on both CK5+ and CK5- cancer cells. by Nadia B. Hassounah (429199)

The decrease in lactate induced by pyruvate is blocked by inhibition of MAS and of the TCA cycle in HKI/HKII double KD cells. by Scott John (228011)

“…This fast inhibitory phase was followed by a sustained one leading to intracellular lactate accumulation (phase 5). …”

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue by Dorota Kmiec (5646374)

“…Here, we show that the Nef protein of the highly divergent SIVcol lineage infecting mantled guerezas (<i>Colobus guereza</i>) is a potent antagonist of SERINC5, although it lacks the CD4, CD3 and CD28 down-modulation activities exerted by other primate lentiviral Nefs. …”

Decreased antihyperglycemic drug use driven by high out-of-pocket costs despite Medicare coverage gap closure by Mugdha Gokhale (8676201)

“…<a><b>Objectives</b></a>: <a>Using the 2016 Medicare part D coverage gap as an example, we explored effects of increased out-of-pocket costs on adherence to branded </a>dipeptidyl peptidase-4 inhibitors (DPP-4i) in patients without financial subsidies, relative to subsidized patients who do not experience increased spending during the gap. …”

Exotic Plant Infestation Is Associated with Decreased Modularity and Increased Numbers of Connectors in Mixed-Grass Prairie Pollination Networks by Diane L. Larson (2793268)

“…Objectives were to compare network-level effects of infestation as they propagate over the season in infested and non-infested (with respect to <i>C</i>. <i>arvense</i>) networks. We characterized plant-pollinator networks on 5 non-infested and 7 infested 1-ha plots during 4 sample periods that collectively covered the length of <i>C</i>. …”

Macroalgae Decrease Growth and Alter Microbial Community Structure of the Reef-Building Coral, <em>Porites astreoides</em> by Rebecca Vega Thurber (41633)

“…To determine if macroalgae alter the coral microbiome, we conducted a field-based experiment in which the coral <em>Porites astreoides</em> was placed in competition with five species of macroalgae. …”

Comparison of SF-36 scores of participants with residual limb pain with a VAS score ≥5 and participants with a VAS score <5. by Martin C. Berli (9427264)

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf by Marta Díaz (337207)

“…</p>Conclusion<p>Early-life changes in circulating exosomes include a minor decrease in size and a major increase in number, and these changes may be influenced by fetal growth. …”

Hookworm infection is associated with decreased CD4⁺ T cell counts in HIV-infected adult Ugandans by Bozena M. Morawski (4047085)

“…Generalized linear models assessed relationships between parasitic infection and clinical or demographic data. 35% of participants (71/202) tested positive for ≥1 helminth, mainly <i>N</i>. <i>americanus</i> (55/199, 28%), and 4.5% (9/202) were infected with ≥2 stool parasites. …”

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand by David Hauton (341981)

“…Hearts of male offspring subjected to Maternal Hypoxia showed a 20% decrease in cardiac output (<i>P</i><0.05), despite recording a 2-fold increase in glucose oxidation (<i>P</i><0.01) and 2.5-fold increase (<i>P</i><0.01) in palmitate oxidation. …”

<i>ING3</i> knockout decreases pan-H4Ac and BRD4 levels and stimulates HIV-1 transcriptional initiation and elongation upon addition of AZD5582. by Emily Hsieh (377992)

“…<p><b>(A)</b> Genome browser tracks centered over the HIV-1 LTR showing the pan-H4Ac signal decreases in the <i>ING3</i> knockout alone and in combination with AZD5582 conditions. …”

Hydroxyl Defects in LiFePO₄ Cathode Material: DFT+<i>U</i> and an Experimental Study by Dmitry A. Aksyonov (4918594)

“…Using a combined computational and experimental approach comprising density functional theory (DFT)+<i>U</i> and molecular dynamics calculations and X-ray and neutron diffraction, we provide a comprehensive characterization of various OH point defects in LiFePO₄, including their formation, dynamics, and localization in the interstitial space and at Li, Fe, and P sites. …”

Chronic Arachidonic Acid Administration Decreases Docosahexaenoic Acid- and Eicosapentaenoic Acid-Derived Metabolites in Kidneys of Aged Rats by Masanori Katakura (816112)

“…In addition, levels of free-form ARA, prostaglandin E₂, and 12- and 15-hydroxyeicosatetraenoic acid increased in the ARA-administered group, whereas renal concentration of docosahexaenoic acid and eicosapentaenoic acid decreased in the ARA-administered group. Levels of docosahexaenoic acid-derived protectin D1, eicosapentaenoic acid-derived 5-, and 18-hydroxyeicosapentaenoic acids, and resolvin E2 and E3 decreased in the ARA-administered group. …”