<i>MAL73</i>, a novel regulator of maltose fermentation, is functionally impaired by single nucleotide polymorphism in <i>sake</i> brewing yeast by Takumi Ohdate (5374196)

“…Here we isolated an ethyl methane sulfonate (EMS)-mutagenized <i>sake</i> yeast strain exhibiting enhanced maltose fermentation compared to the parental strain. …”

Data_Sheet_1_Comparative Effectiveness of Multiple Psychological Interventions for Psychological Crisis in People Affected by Coronavirus Disease 2019: A Bayesian Network Meta-Anal... by Yang Yang (45629)

“…</p><p>Result: Sixteen self-controlled case series (SCCS) comprising 1,147 participants compared five different psychological interventions with four different measurement scales were included in this study. …”

The genetic architecture of larval aggregation behavior in <i>Drosophila</i> by Ross M. McKinney (10195283)

“…Results from single gene, RNAi-knockdown experiments show that several of the identified genes represent key nodes in the genetic network that determines the level of aggregation while feeding. Furthermore, we show that a single non-coding variant in the gene <i>CG14205</i>, a putative acyltransferase, is associated with both decreased mRNA expression and increased aggregate formation, which suggests that it has a specific role in inhibiting aggregation behavior. …”

The Vitamin D Receptor Inhibits the Respiratory Chain, Contributing to the Metabolic Switch that Is Essential for Cancer Cell Proliferation by Marco Consiglio (275917)

“…VDR knockdown resulted in robust growth inhibition, with accumulation in the G0G1 phase of the cell cycle and decreased accumulation in the M phase. …”

Image5_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF by Zhengxin Ma (6309152)

“…Here, we investigated the role of the ISR during nutrient limitation and ER stress with respect to changes in protein synthesis, translationally driven mRNA turnover, and survival in Caenorhabditis elegans. …”

Dynamin inhibition reduces apoE secretion from liver cells. by Maaike Kockx (154125)

Construction of <i>sf3b1-H698D</i> and <i>-H698R</i> mutant strains. by Bei Zhang (428038)

Image_5_Online adaptive group-wise sparse Penalized Recursive Exponentially Weighted N-way Partial Least Square for epidural intracranial BCI.JPEG by Alexandre Moly (14721733)

“…Three types of sparsity-promoting penalization were explored using L_pwith p = 0., 0.5, and 1.</p>Results<p>The algorithms were tested offline in a pseudo-online manner for features grouped by spatial dimension. …”

Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

Table_1_SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.xlsx by Helene Sertznig (9649127)

“…Type I interferons (IFN-I) play a crucial role in the innate immunity against HIV-1 by inducing the expression of IFN-stimulated genes (ISGs) including potent host restriction factors. …”

Table_1_A Partially Phase-Separated Genome Sequence Assembly of the Vitis Rootstock ‘Börner’ (Vitis riparia × Vitis cinerea) and Its Exploitation for Marker Development and Targete... by Daniela Holtgräwe (642655)

“…<p>Grapevine breeding has become highly relevant due to upcoming challenges like climate change, a decrease in the number of available fungicides, increasing public concern about plant protection, and the demand for a sustainable production. …”

Table1_Herb-Drug Interaction Between Xiyanping Injection and Lopinavir/Ritonavir, Two Agents Used in COVID-19 Pharmacotherapy.DOCX by Linhu Ye (10119425)

“…However, the pharmacokinetic parameters of RTV were significantly changed after pretreatment with XYPI, particularly in treatment for seven consecutive days, the AUC_0-∞ of RTV was significantly shifted from 0.69 to 2.72 h μg/mL (p < 0.05) and the CL exhibited a tendency to decrease from 2.71 L/h to 0.94 L/h (p < 0.05), and the t_1/2 of RTV prolonged from 3.70 to 5.51 h (p < 0.05), in comparison with the corresponding parameters in untreated rats. …”

Influence of Si Coating on Interfacial Microstructure of Laser Joining of Titanium and Aluminium Alloys by Aline Capella de Oliveira (4654930)

“…EDS line scanning in the joining interface showed a reduction of compound layer thickness, considering the silicon as interlayer, reaching the mean value of 3 µm, i.e., up to five times thinner if compared to joining without silicon during the process.…”

Influence of Si Coating on Interfacial Microstructure of Laser Joining of Titanium and Aluminium Alloys by Aline Capella de Oliveira (4654930)

“…EDS line scanning in the joining interface showed a reduction of compound layer thickness, considering the silicon as interlayer, reaching the mean value of 3 µm, i.e., up to five times thinner if compared to joining without silicon during the process.…”

Table_2_The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction.docx by Mahmoud B. Maina (5593007)

“…These markers of cellular dysfunction worsen over time alongside a reduction in ribosomal RNA synthesis and processing, a decrease in global level of newly synthesized RNA and reduced protein synthesis. …”

DataSheet1_Melatonin Maintains Anabolic-Catabolic Equilibrium and Regulates Circadian Rhythm During Osteoarthritis Development in Animal Models: A Systematic Review and Meta-analys... by Dewan Md. Sumsuzzman (11447752)

“…Compared with the control group, MT significantly decreased the levels of interleukin-1β (IL-1β; SMD = −5.45; 95% CI [−6.78, −4.12]; p < 0.00001, and histological grading scale (SMD = −3.46; 95% CI, [−5.24, −1.68]; p < 0.0001). …”

Loss of <i>Ccbe1</i> affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells by Oriol Bover (5815112)

“…Disruption of <i>Ccbe1</i> activity by shRNA knockdown or blockade with a neutralizing antibody results in impaired differentiation of embryonic stem cells along the cardiac mesoderm lineage resulting in a decreased expression of mature cardiomyocyte markers. …”

Table_5_Antimicrobial resistance and clonality of Staphylococcus aureus causing bacteraemia in children admitted to the Manhiça District Hospital, Mozambique, over two decades.doc by Marcelino Garrine (843693)

“…The CC152, initially detected in 2001, re-emerged in 2010 and became predominant throughout the remaining surveillance period, while other CCs (CC1, CC5, CC8, CC15, CC25, CC80, and CC88) decreased over time. …”

In <i>Drosophila</i>, Gr64f promotes feeding. by Di Guo (718480)

“…(<b>E</b>) Silencing the <i>Gr64f</i> gene using the Gr5a-GAL4 driver leads to decreased food consumption compared to wildtype flies in the CAFE essay. …”

Prefrontal cortex-dependent innate behaviors are altered by selective knockdown of <i>Gad1</i> in neuropeptide Y interneurons by Katelynn M. Corder (5537507)

“…However, the role of GABA release from NPY+ interneurons in adolescent anxiety is unclear. Here we used a transgenic mouse that reduces GAD67 in NPY+ cells (NPYGAD1-TG) through G<i>ad1</i> knockdown and tested for effects on behavior in adolescent mice. …”