Table_2_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…The BAL samples were harvested 24 h after ozone (2 ppm for 3 h) or FA exposure and infection and analyzed by two-dimensional difference gel electrophoresis (2D-DIGE) and MALDI-ToF/ToF. We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Table_3_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…The BAL samples were harvested 24 h after ozone (2 ppm for 3 h) or FA exposure and infection and analyzed by two-dimensional difference gel electrophoresis (2D-DIGE) and MALDI-ToF/ToF. We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Lethality from cecal ligation and puncture (CLP) is decreased in BALB/c mice administered an anti-RAGE monoclonal antibody (mAb) by Emily C Lutterloh (87191)

2-AAPA decreases H/R induced apoptosis in mitoNEET-KD cells and increases mitoNEET-protein despite KD. by Anika Habener (3165984)

“…(B) siRNA transfection decreased mitoNEET-mRNA efficiently in the presence and absence of chemical GSR-inhibitor 2-AAPA (10 μM, n = 5) determined by real-time RT-PCR. …”

HGDP data show that T2D risk allele frequencies decrease from Sub-Saharan Africa through Europe to East Asia. by Rong Chen (29176)

“…A similar pattern was observed in the remaining five T2D risk alleles in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002621#pgen.1002621.s002" target="_blank">Figure S2</a>. …”

Preliminary Evidence for Cell Membrane Amelioration in Children with Cystic Fibrosis by 5-MTHF and Vitamin B12 Supplementation: A Single Arm Trial by Cinzia Scambi (243788)

“…In CF children, 5-MTHF and vitamin B12 supplementation (i) increased plasma and RBC folate levels; (ii) decreased plasma homocysteine levels; (iii) modified RBC membrane phospholipid fatty acid composition; (iv) increased RBC K⁺ content; (v) reduced RBC membrane oxidative damage and HSP70 membrane association.…”

Total CD34+KDR+ cells across pregnancy and postpartum in control, type 1 and type 2 diabetic women. by Patricia D. A. Lima (707898)

Effect of metformin exposure on growth and photosynthetic performance in the unicellular freshwater chlorophyte, <i>Chlorella vulgaris</i> by Brittany M. Cummings (5954474)

“…However, effects of metformin on aquatic primary producers are poorly known. We exposed cultured isolates of a freshwater chlorophyte, <i>Chlorella vulgaris</i>, to a range of metformin concentrations (0–767.9 mg L^-1) to test the hypothesis that exposure negatively affects photosynthesis and growth. …”

DataSheet_1_LINC00460 Is a Dual Biomarker That Acts as a Predictor for Increased Prognosis in Basal-Like Breast Cancer and Potentially Regulates Immunogenic and Differentiation-Rel... by Mireya Cisneros-Villanueva (10585697)

“…LINC00460 can also modulate a plethora of immunogenic related genes in BRCA, such as SFRP5, FOSL1, IFNK, CSF2, DUSP7 and IL1A and interacts with miR-103-a-1, in-silico, which, in turn, can no longer target WNT7A. …”

TP compounds suppress tumor growth, decrease cell proliferation and induce caspase 3 cleavage in mouse xenograft models with no systemic toxicities. by Melissa Millard (275631)

“…<p>(A) Graph shows average tumor volumes amongst the treatment groups over the course of the experiment. …”

Total Circulating Progenitor Cell (CPC) analysis through pregnancy and postpartum in control, type 1 and type 2 diabetic women. by Patricia D. A. Lima (707898)

DataSheet1_ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis.PDF by Sergey Nikulin (7839071)

“…Previously we have shown that low expression of ELOVL5 and IGFBP6 genes in breast cancer tissue corresponded to poor prognosis. …”

<i>L</i>. <i>interrogans</i> requires both PerRA and PerRB for renal colonization of C3H/HeJ mice. by André A. Grassmann (11141592)

Table_2_Tumor-Acidity Responsive Polymeric Nanoparticles for Targeting Delivery of Angiogenesis Inhibitor for Enhanced Antitumor Efficacy With Decreased Toxicity.docx by Xiufeng Cong (10361204)

“…<p>Various nanocarriers with tumor targeting ability and improved pharmacokinetic property have been extensively utilized to reduce the toxicity of existing clinical chemotherapeutics. Herein, we showed that by encapsulating angiogenesis inhibitor anlotinib into polymeric nanoparticles, we could significantly decrease its in vivo toxicity. …”

MR sequences during supine bicycle exercise-induced stress protocol. by Laurence Bal-Theoleyre (2839193)

Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5 by Li-Yun Huang (3141372)

“…Poly(I:C) increased endothelial monolayer permeability with a corresponding dose- and time-dependent decrease in the expression of claudin-5, a transmembrane tight junction protein and reduction of <i>CLDN5</i> mRNA levels. …”

Image_1_NFAT5 Isoform C Controls Biomechanical Stress Responses of Vascular Smooth Muscle Cells.tif by Maren Zappe (5678081)

“…Detailed PCR analyses indicated a decrease in expression of NFAT5 isoform A and an increase in isoform C in mechanoactivated VSMCs. …”

Poly(DEAEMa-<i>c</i><i>o</i>-PEGMa):  A New pH-Responsive Comb Copolymer Stabilizer for Emulsions and Dispersions by Sheikh Shahalom (2526943)

“…The emulsions consisted of tetradecane-in-water and had a droplet size in the range 5−11 μm. They were slightly flocculated when the pH value was close to the isoelectric point. …”

Functionnal MRI methodology. by Laurence Bal-Theoleyre (2839193)

Data_Sheet_1_His-Ala-Phe-Lys peptide from Burkholderia arboris possesses antifungal activity.docx by Huajie Zhu (2228854)

“…Furthermore, a comparison of the differential metabolites between wild type B. arboris and the ∆cobA mutant showed a significantly decreased level of tetrapeptide His-Ala-Phe-Lys (Hafk) in the ∆cobA mutant. …”