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19861
Targeted disruption of murine SLD5 and expression of SLD5 during early embryogenesis.
Published 2013“…<p>(A) Generation of SLD5-deficient mice. Exons of SLD5 were replaced by homologous recombination with a β-galactosidase-encoding gene (lacZ) fused to a neomycin resistance gene driven by the MC1 promoter (Neo). …”
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19862
LV function and geometry: Exercise cohort.
Published 2024“…Additionally, miR-22 and miR-30e decreased with exercise and mapped to a localized inflammatory process, the inflammasome (NLRP-3, whereby a 2-fold decrease in NLRP-3 mRNA occurred with exercise (p < 0.05).…”
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19863
S1 Graphical abstract -
Published 2024“…Additionally, miR-22 and miR-30e decreased with exercise and mapped to a localized inflammatory process, the inflammasome (NLRP-3, whereby a 2-fold decrease in NLRP-3 mRNA occurred with exercise (p < 0.05).…”
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19864
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19865
Increase in conjunctival AQP5 and MUC5AC expression in rabbits after surgery.
Published 2017“…The MUC5AC protein expression followed similar pattern of upregulation, demonstrating a synchronous relationship with AQP5. …”
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19866
Data_Sheet_2_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.docx
Published 2019“…The BAL samples were harvested 24 h after ozone (2 ppm for 3 h) or FA exposure and infection and analyzed by two-dimensional difference gel electrophoresis (2D-DIGE) and MALDI-ToF/ToF. We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”
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19867
Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease
Published 2025“…<i>In vivo</i>, <b>A1</b> showed a strong anti-inflammatory activity in acute enteritis models and decreased the release of various proinflammatory factors, including IL-6 and TNF-α. …”
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19868
Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease
Published 2025“…<i>In vivo</i>, <b>A1</b> showed a strong anti-inflammatory activity in acute enteritis models and decreased the release of various proinflammatory factors, including IL-6 and TNF-α. …”
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19869
Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease
Published 2025“…<i>In vivo</i>, <b>A1</b> showed a strong anti-inflammatory activity in acute enteritis models and decreased the release of various proinflammatory factors, including IL-6 and TNF-α. …”
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19870
Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease
Published 2025“…<i>In vivo</i>, <b>A1</b> showed a strong anti-inflammatory activity in acute enteritis models and decreased the release of various proinflammatory factors, including IL-6 and TNF-α. …”
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19871
Image_3_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.PNG
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19872
Table_6_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.XLS
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19873
Table_4_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.XLSX
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19874
Table_3_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.XLS
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19875
Image_2_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.JPEG
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19876
Table_2_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.XLS
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19877
Image_4_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.JPEG
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19878
Protective Effect of Combined Metoprolol and Atractylenolide I in Rats with Acute Myocardial Infarction via Modulation of the SIRT3/β-CATENIN/PPAR-γ Signaling Pathway
Published 2023“…<div><p>ABSTRACT Herein, we examined the protective effect of metoprolol combined with atractylenolide I (Atr I) in acute myocardial infarction (AMI) by regulating the SIRT3 (silent information regulator 3)/β-catenin/peroxisome proliferator-activated receptor gamma (PPAR-γ) signaling pathway. …”
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19879
RSV inhibited the interaction of klf5 with c-Myc by inducing klf5 phosphorylation.
Published 2017“…<p>Cultured HEK293 cells were incubated with 20 μM RSV for different times, and then subjected to western blot analysis. (A) Cell extracts were immunoprecipitated with antibody to phosphoserine and immunoblotted with antibody to klf5. …”
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19880
Network fusion.
Published 2023“…(e) For a varying threshold of strongest edges (0.5%–5% in 0.5% intervals), we calculate the proportion of edges that connect 2 regions within the same intrinsic network (left), cytoarchitectonic class (middle), and the union of intrinsic networks and cytoarchitectonic classes (right). …”