Table_5_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Allelic loss of <i>Cdh11</i> led to faster growing tumors due to decreased cell death. by Mellone N. Marchong (249928)

“…(D) To further support this data, we analyzed for the expression of five pro-apoptotic proteins (activated caspase-3, 8, 9, Trail and Bax) in an additional cohort of <i>Cdh11^+/+;TAg^+/-</i> and <i>Cdh11^-/-;TAg^+/-</i> PND84 animals. …”

Image5_Vaccine induced mucosal and systemic memory NK/ILCs elicit decreased risk of SIV/SHIV acquisition.jpeg by Mohammad Arif Rahman (8267352)

“…<p>SIV and HIV-based envelope V1-deleted (ΔV1) vaccines, delivered systemically by the DNA/ALVAC/gp120 platform, decrease the risk of mucosal SIV or SHIV acquisition more effectively than V1-replete vaccines. …”

B-factor values of Ca_V3.3 M1425 substitutions. by Yousra El Ghaleb (22075892)

Subjects:

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Video_5_Decreased levels of discomfort in repeatedly handled mice during experimental procedures, assessed by facial expressions.MP4 by Julia Swan (14556800)

Video_5_Decreased levels of discomfort in repeatedly handled mice during experimental procedures, assessed by facial expressions.MP4 by Julia Swan (14556800)

Effects of SNPs on the Protein Stability, Increasing or Decreasing. by Mirza Jawad Ul Hasnain (8351388)

The influence of the controlled pH conditions at the sample preparation step on the obtained signals (panel A: extraction using a mixture of MeOH and EtOH; panel B: extraction usin... by Ewa Paszkowska (21246702)

The phosphorylation sites we identified in both ULK1 and ATG13 are conserved between different isoforms. by Zhiyuan Li (205620)

DataSheet_1_Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma.pdf by Juan José Nieto-Fontarigo (11800142)

“…</p>Methods<p>Effects of imiquimod alone were examined in HBECs from healthy (N=4) and asthmatic (N=18) donors. Mimicking SARS-CoV-2 infection, HBECs were stimulated with poly(I:C), a dsRNA analogue, or SARS-CoV-2 spike-protein 1 (SP1; receptor binding) with and without imiquimod treatment. …”

FOXO1-mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys by Mengru Zeng (10119544)

“…Overexpression of RAB27B restored exosome secretion in HG-treated cells, suggesting a role of RAB27B downregulation in the decrease of exosome secretion in DKD. To understand the mechanism of RAB27B downregulation, we conducted bioinformatics analysis that identified FOXO1 binding sites in the Rab27b gene promoter. …”

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)

Five main steps of MATSim. by Jingfa Ma (20396406)

“…Results indicate that enhancements in vehicle range and charging efficiency slightly decrease the use of autonomous vehicles by 2.5%, as the existing vehicle specifications already meet daily travel needs in Shanghai. …”

Decrease in I_Na caused by I_leak versus the NEP. by Lisha Yang (1695241)

Data_Sheet_1_Artesunate Alleviates Paclitaxel-Induced Neuropathic Pain in Mice by Decreasing Metabotropic Glutamate Receptor 5 Activity and Neuroinflammation in Primary Sensory Neu... by Yize Li (471459)

“…Artesunate normalized paclitaxel-related expression changes in DRG mGluR5, NR1, and GluA2, as well as six paclitaxel related neuroinflammation markers. …”

Isotonic Glycerol and Sodium Hyaluronate Containing Artificial Tear Decreases Conjunctivochalasis after One and Three Months: A Self-Controlled, Unmasked Study by Huba J. Kiss (769411)

“…Conjunctivochalasis decreased from a mean LIPCOF degree of 2.9±0.4 on both eyes to 1.4±0.6 on the right (median decrease of -2 points, 95% CI from -2.0 to -1.0), and to 1.4±0.7 on the left eye (median decrease of -1 points, 95% CI from -2.0 to -1.0) (p<0.001 for both sides). …”