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721
Optical Effects of <i>S</i>-Oxidation and M<sup><i>n</i>+</sup> Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl...
Published 2008“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu<sup>2+</sup> addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M<sup>2+</sup> binding; for Hg<sup>2+</sup> 1:2 substrate:M<sup>2+</sup> binding was found. …”
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722
Optical Effects of <i>S</i>-Oxidation and M<sup><i>n</i>+</sup> Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl...
Published 2008“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu<sup>2+</sup> addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M<sup>2+</sup> binding; for Hg<sup>2+</sup> 1:2 substrate:M<sup>2+</sup> binding was found. …”
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723
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724
Table_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx
Published 2022“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”
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725
Image_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif
Published 2022“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”
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726
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727
Data_Sheet_1_Methamphetamine signals transcription of IL1β and TNFα in a reactive oxygen species-dependent manner and interacts with HIV-1 Tat to decrease antioxidant defense mecha...
Published 2022“…We found that this effect occurred via the activation of the activator protein 1 (AP-1) comprising cFOS and cJUN transcription factors and regulated by the SRC kinase. …”
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728
Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology
Published 2018“…Across 5,804 individuals of European ancestry from two studies, we found strong evidence, using PRS, of genetic overlap between nsCL/P and philtrum width; a 1 S.D. increase in nsCL/P PRS was associated with a 0.10 mm decrease in philtrum width (95% C.I. 0.054, 0.146; P = 2x10<sup>-5</sup>). …”
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729
Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease
Published 2011“…Kidney angiomyolipomas regrew when sirolimus was discontinued but responses tended to persist if treatment was continued after week 52. We observed regression of brain tumors (SEGAs) in 7/11 cases (26% mean decrease in diameter), regression of liver angiomyolipomas in 4/5 cases (32.1% mean decrease in longest diameter), subjective improvement in facial angiofibromas in 57%, and stable lung function in women with TSC/LAM (n = 15). …”
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730
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731
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732
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733
Use of the 9-item Shared Decision Making Questionnaire (SDM-Q-9 and SDM-Q-Doc) in intervention studies—A systematic review
Published 2017“…</p><p>Methods</p><p>We conducted a systematic review of studies published between 2010 and October 2015 that evaluated interventions to facilitate SDM. …”
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734
Glibenclamide Decreases ATP-Induced Intracellular Calcium Transient Elevation via Inhibiting Reactive Oxygen Species and Mitochondrial Activity in Macrophages
Published 2014“…Glibenclamide also decreased the peak of [Ca<sup>2+</sup>]<sub>i</sub> transient induced by extracellular thapsigargin (Tg, 1 µM). …”
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735
Crystal structures of Triosephosphate Isomerases from <i>Taenia solium</i> and <i>Schistosoma mansoni</i> provide insights for vaccine rationale and drug design against helminth pa...
Published 2020“…Surprisingly, the epitopes corresponding to the SXD/E inserts are not the ones with the greatest immunological potential. SmTPI, but not TsTPI, habors a sole solvent exposed cysteine (SmTPI-S230) and alterations in this residue decrease catalysis. …”
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736
Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis
Published 2018“…We found statistically noticeable decreased richness, and increased dissimilarity in the antibiotic, but not in the placebo group after therapy. …”
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737
Table_1_Elevated hypertriglyceridemia and decreased gallstones in the etiological composition ratio of acute pancreatitis as affected by seasons and festivals: A two-center real-wo...
Published 2022“…The composition ratio of HTG-AP increased, while gallstone AP decreased in winter and in months with long holidays (all P<0.01). …”
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738
Microwave hyperthermia enhances radiosensitization by decreasing DNA repair efficiency and inducing oxidative stress in PC3 prostatic adenocarcinoma cells
Published 2024“…</p> <p>We developed a dedicated MW-HT heating setup, created an <i>in vitro</i> and <i>in vivo</i> MW-HT + RT treatment model for CRPC. …”
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739
The role of AGEs in high glucose-induced voltage-gated K<sup>+</sup> (K<sub>v</sub>) channels dysfunction in vascular smooth muscle cells (VSMCs).
Published 2015“…B: I-V relationships of K<sub>v</sub> current density in VSMCs. …”
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740
Controlling the Temperature and Speed of the Phase Transition of VO<sub>2</sub> Microcrystals
Published 2016“…As the width of square cylinder-shaped microcrystals decreases from ∼70 to ∼1 μm, the phase transition temperature (67 °C for bulk) varied as much as 26.1 °C (19.7 °C) during heating (cooling). …”