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19861
Enhanced survival following oral and systemic <i>Salmonella enterica</i> serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice
Published 2018“…Separately, we infected mice either orally or intravenously (IV) with <i>S</i>. …”
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19862
The Response of the Alpine Dwarf Shrub <i>Salix herbacea</i> to Altered Snowmelt Timing: Lessons from a Multi-Site Transplant Experiment
Published 2015“…We tested how the common, long-lived dwarf shrub <i>Salix herbacea</i> responded to changing spring snowmelt time by reciprocally transplanting turfs of <i>S</i>. …”
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19863
Image_2_Restored CD8+PD-1+ T Cells Facilitate the Response to Anti-PD-1 for Patients With Pancreatic Ductal Adenocarcinoma.jpeg
Published 2022“…The peripheral blood T lymphocyte subtypes were tracked for 30 months, and CD8<sup>+</sup>PD-1<sup>+</sup> cells were shown to decrease. After that, we performed ACT for patients with APC in another cancer center. …”
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19864
p53 Target Gene SMAR1 Is Dysregulated in Breast Cancer: Its Role in Cancer Cell Migration and Invasion
Published 2007“…We show that SMAR1 transcription is regulated by p53 through its response element present in the SMAR1 promoter. …”
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19865
Trends in the risk of myocardial infarction among HIV-1-infected individuals relative to the general population in France: Impact of gender and immune status
Published 2019“…<div><p>We examined trends in the MI incidence and age at MI diagnosis among adults living with HIV-1 between 2000 and 2009, by comparison with the French MI registries, by gender. …”
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19866
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies
Published 2024“…We discovered two new GPR88 agonists: One that reduced morphine-induced locomotor activity in a murine proof-of-concept study, and the atropoisomeric BI-9508, which is a brain penetrant and has improved pharmacokinetic properties and dosing that recommend it for future <i>in vivo</i> studies in rodents. …”
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19867
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies
Published 2024“…We discovered two new GPR88 agonists: One that reduced morphine-induced locomotor activity in a murine proof-of-concept study, and the atropoisomeric BI-9508, which is a brain penetrant and has improved pharmacokinetic properties and dosing that recommend it for future <i>in vivo</i> studies in rodents. …”
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19868
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies
Published 2024“…We discovered two new GPR88 agonists: One that reduced morphine-induced locomotor activity in a murine proof-of-concept study, and the atropoisomeric BI-9508, which is a brain penetrant and has improved pharmacokinetic properties and dosing that recommend it for future <i>in vivo</i> studies in rodents. …”
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19869
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies
Published 2024“…We discovered two new GPR88 agonists: One that reduced morphine-induced locomotor activity in a murine proof-of-concept study, and the atropoisomeric BI-9508, which is a brain penetrant and has improved pharmacokinetic properties and dosing that recommend it for future <i>in vivo</i> studies in rodents. …”
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19870
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies
Published 2024“…We discovered two new GPR88 agonists: One that reduced morphine-induced locomotor activity in a murine proof-of-concept study, and the atropoisomeric BI-9508, which is a brain penetrant and has improved pharmacokinetic properties and dosing that recommend it for future <i>in vivo</i> studies in rodents. …”
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19871
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies
Published 2024“…We discovered two new GPR88 agonists: One that reduced morphine-induced locomotor activity in a murine proof-of-concept study, and the atropoisomeric BI-9508, which is a brain penetrant and has improved pharmacokinetic properties and dosing that recommend it for future <i>in vivo</i> studies in rodents. …”
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19872
Geometrical Constraints Greatly Hinder Formin mDia1 Activity
Published 2019“…Combining microfluidics and micropatterning, we reconstituted in vitro mDia1 formin-elongated filament bundles induced by fascin, with different geometrical constraints on the formins, and measured the impact of these constraints on formin elongation rate and processivity. …”
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19873
Geometrical Constraints Greatly Hinder Formin mDia1 Activity
Published 2019“…Combining microfluidics and micropatterning, we reconstituted in vitro mDia1 formin-elongated filament bundles induced by fascin, with different geometrical constraints on the formins, and measured the impact of these constraints on formin elongation rate and processivity. …”
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19874
Geometrical Constraints Greatly Hinder Formin mDia1 Activity
Published 2019“…Combining microfluidics and micropatterning, we reconstituted in vitro mDia1 formin-elongated filament bundles induced by fascin, with different geometrical constraints on the formins, and measured the impact of these constraints on formin elongation rate and processivity. …”
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19875
Geometrical Constraints Greatly Hinder Formin mDia1 Activity
Published 2019“…Combining microfluidics and micropatterning, we reconstituted in vitro mDia1 formin-elongated filament bundles induced by fascin, with different geometrical constraints on the formins, and measured the impact of these constraints on formin elongation rate and processivity. …”
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19876
Regulatory Protein OmpR Influences the Serum Resistance of <i>Yersinia enterocolitica</i> O:9 by Modifying the Structure of the Outer Membrane
Published 2013“…We propose that OmpR might alter the susceptibility of <i>Y. enterocolitica</i> O:9 to complement-mediated killing through remodeling of the outer membrane.…”
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19877
Integrating Paleodistribution Models and Phylogeography in the Grass-Cutting Ant <i>Acromyrmex striatus</i> (Hymenoptera: Formicidae) in Southern Lowlands of South America
Published 2016“…From the partial sequences of the mitochondrial gene cytochrome oxidase I of 128 <i>A</i>. <i>striatus</i> workers from 38 locations we estimated genetic diversity and inferred historical demography, divergence time, and population structure. …”
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19878
Supplementary Table 3 from <i>Pendraig milnerae</i>, a new small-sized coelophysoid theropod from the Late Triassic of Wales
Published 2021“…We describe a new small-bodied coelophysoid theropod dinosaur, <i>Pendraig milnerae</i> gen. et sp. nov, from the Late Triassic fissure fill deposits of Pant-y-ffynnon in southern Wales. …”
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19879
DataSheet1_Evaluation of the efficacy of mitochondrial fission inhibitor (Mdivi-1) using non-alcoholic steatohepatitis (NASH) liver organoids.docx
Published 2023“…Treatment of NLO with a DPR1 inhibitor, Mdivi-1 resulted in the improvement of morphology and the decreased expression of fibrosis-related markers, Col1a1 and Acta2. …”
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19880
DNMT1-mediated demethylation of lncRNA MEG3 promoter suppressed breast cancer progression by repressing Notch1 signaling pathway
Published 2022“…In addition, we found that MEG3 expression was negatively correlated with DNMT1. …”