HTRF for high-throughput screening of HCMV NEC inhibitors. by Han Chen (228557)

“…The HTRF ratio for the NEC (signal, S) was ~3-fold higher than the background (B) HTRF ratios for His-UL50 or Myc-UL53 alone (S/B ~3). Untagged UL50 decreased S/B to near background levels, serving as a positive control, while UL50_E56A, which is highly defective for UL53 binding [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011781#ppat.1011781.ref012" target="_blank">12</a>] did not decrease S/B, serving as a negative control. …”

Presentation_1_Correlation Between Anti-gp41 Antibodies and Virus Infectivity Decay During Primary HIV-1 Infection.PDF by Naveen K. Vaidya (170290)

“…<p>Recent experiments have suggested that the infectivity of simian immunodeficiency virus (SIV) and human immunodeficiency virus type-1 (HIV-1) in plasma decreases over time during primary infection. …”

Table_1_Axitinib Reverses Resistance to Anti-Programmed Cell Death-1 Therapy in a Patient With Renal Cell Carcinoma.xls by Yonghao Yang (3415943)

“…However, she finally achieved a partial response with a continuous combination therapy comprising low-dose axitinib and anti-PD-1. We speculate that axitinib played a key role in reversing the primary resistance to anti-PD-1 therapy. …”

Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in <i>Dictyostelium discoideum</i>, independent of PSEN (presenilin) proteolytic function by Devdutt Sharma (6399806)

“…Importantly, we find that all the endocytic defects observed in <i>Dictyostelium</i> PSEN ortholog mutants can be fully rescued by proteolytically inactive <i>Dictyostelium</i> psenB and human PSEN1 proteins. …”

<i>Cephalaria transsylvanica</i>-Based Flower Strips as Potential Food Source for Bees during Dry Periods in European Mediterranean Basin Countries by Giovanni Benelli (521608)

“…<div><p>The introduction of sown wildflower strips favours the establishment of pollinator communities, with special reference to social Apoidea. Here, we evaluated the late summer flowering <i>Cephalaria transsylvanica</i> as suitable species for strips providing food for pollinators in paucity periods. …”

Reduced Parasite Motility and Micronemal Protein Secretion by a p38 MAPK Inhibitor Leads to a Severe Impairment of Cell Invasion by the Apicomplexan Parasite <i>Eimeria tenella</i> by Françoise I. Bussière (692733)

“…Our objective was to determine the importance of these kinases on cell invasion by <i>E</i>. <i>tenella</i>. We evaluated the effect of specific inhibitors (ERK: PD98059, JNKII: SP600125, p38 MAPK: SB203580) on the invasion of epithelial cells. …”

Price History 21.10.19 (1).xlsx by Mikhaylov (7525328)

Different construction strategies affected on the physiology of <i>Pichia pastoris</i> strains highly expressed lipase by transcriptional analysis of key genes by Jinjin Huang (5461844)

“…We observed that (i) Addition of propeptide decreased lipase folding stress by down-regulated four UPR-related genes. …”

Data_Sheet_1_Topography and Tilt at Volcanoes.PDF by Luke H. Marsden (7329320)

Data_Sheet_1_Topography and Tilt at Volcanoes.PDF by Luke H. Marsden (7329320)

Impact of Dietary Tomato Juice on Changes in Pulmonary Oxidative Stress, Inflammation and Structure Induced by Neonatal Hyperoxia in Mice (<i>Mus musculus</i>) by Sheena Bouch (3149889)

“…At P7d and P56d, we analyzed total antioxidant capacity (TAC), markers of oxidative stress (nitrotyrosine and <i>heme oxygenase-1</i> expression), inflammation (<i>interleukin-1β</i> (<i>IL-1β</i>) and <i>tumor necrosis factor-α</i> (<i>TNF-α</i>) expression), collagen (<i>COL</i>) and smooth muscle in the lungs; we also assessed lung structure. …”

Image_2_Functional Status of Neuronal Calcium Sensor-1 Is Modulated by Zinc Binding.TIF by Philipp O. Tsvetkov (196284)

“…Meanwhile, one of the EF-hands of Zn²⁺-saturated NCS-1 exhibits a 14-fold higher calcium affinity, which increases the overall calcium sensitivity of the protein. …”

Data_Sheet_1_DYT1 Dystonia Patient-Derived Fibroblasts Have Increased Deformability and Susceptibility to Damage by Mechanical Forces.PDF by Navjot Kaur Gill (6877559)

“…We observe a similar increased deformability of mouse fibroblasts that lack lamina-associated polypeptide 1 (LAP1), which interacts with and stimulates the ATPase activity of torsinA in vitro, as well as with the absence of the LINC complex proteins, Sad1/UNC-84 1 (SUN1) and SUN2, lamin A/C, or lamin B1. …”

DataSheet1_Luteolin induces pyroptosis in HT-29 cells by activating the Caspase1/Gasdermin D signalling pathway.PDF by Yiliu Chen (13502296)

“…However, the Caspase1 inhibitor VX765 did reverse the inhibition of cell growth. …”

DataSheet_1_FGL1 as a Novel Mediator and Biomarker of Malignant Progression in Clear Cell Renal Cell Carcinoma.pdf by Zheng Lv (5781647)

“…We found that FGL1 was upregulated in tumor tissues and plasma specimens of ccRCC patients. …”

Constructing Asymmetrical Ni-Centered {NiN₂O₄} Octahedra in Layered Metal–Organic Structures for Near-Room-Temperature Single-Phase Magnetoelectricity by Kaihui Mao (9110845)

“…The change in ME polarization with increasing applied magnetic field μ₀<i>H</i> from 0 to 2 T decreases linearly from 0.041 to 0.011 μC/cm² at the strongest ME coupling temperature of 251 K. …”

Constructing Asymmetrical Ni-Centered {NiN₂O₄} Octahedra in Layered Metal–Organic Structures for Near-Room-Temperature Single-Phase Magnetoelectricity by Kaihui Mao (9110845)

“…The change in ME polarization with increasing applied magnetic field μ₀<i>H</i> from 0 to 2 T decreases linearly from 0.041 to 0.011 μC/cm² at the strongest ME coupling temperature of 251 K. …”

Constructing Asymmetrical Ni-Centered {NiN₂O₄} Octahedra in Layered Metal–Organic Structures for Near-Room-Temperature Single-Phase Magnetoelectricity by Kaihui Mao (9110845)

“…The change in ME polarization with increasing applied magnetic field μ₀<i>H</i> from 0 to 2 T decreases linearly from 0.041 to 0.011 μC/cm² at the strongest ME coupling temperature of 251 K. …”

Constructing Asymmetrical Ni-Centered {NiN₂O₄} Octahedra in Layered Metal–Organic Structures for Near-Room-Temperature Single-Phase Magnetoelectricity by Kaihui Mao (9110845)

“…The change in ME polarization with increasing applied magnetic field μ₀<i>H</i> from 0 to 2 T decreases linearly from 0.041 to 0.011 μC/cm² at the strongest ME coupling temperature of 251 K. …”

Comparison of <i>Killer-Rescue</i> and split <i>ClvR</i> genetics. by Georg Oberhofer (3401438)