Tear stability is decreased in <i>Muc5ac</i>-deficient mice (KO) compared to wild-type mice (WT). by Anne M. Floyd (293362)

ASO treatment suppresses the palbociclib-mediated induction of MEG3 and decrease in cell proliferation in A549 cells. by Traci L. Kruer (3342425)

The A1 mutation decreases antisense transcriptional activity of the LTR in OVK cells. by Thomas Joris (13224720)

Disruption of Spatacsin decreases the regeneration of lysosomes in KO MEFs. by Rita-Eva Varga (784560)

“…<p><b>(A, G, K)</b> Autolysosomes defined as vesicles that stain for both Lamp1 and p62 are increased in KO compared to WT MEFs (Mean±SEM of n = 3 experiments; Student’s t-test: ** indicates p<0.01). …”

CD148 knockdown reduces cell-cell adhesion and E-cadherin contacts accompanied by a decrease in Rac1 activity in A431 cells. by Keiko Takahashi (375228)

Inactivation of Rb leads to decreased expression of MEG3 and re-expression inhibits proliferation in A549 cells. by Traci L. Kruer (3342425)

Nrf2 activation decreases PMN ROS production in response to zymosan. by Doumet Georges Helou (7255823)

ZfpA overexpression decreases voriconazole efficacy <i>in vitro</i> and during infection. by Taylor J. Schoen (15383519)

MMS induces an Aag-dependent decrease in motor function. by Jennifer A. Calvo (399096)

mTOR activity is decreased in KSR1-deficient T cells. by Marie Le Borgne (337225)

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”

Loss of FOXP1 results in decreased number of bRGCs. by Seon Hye E. Park (16765033)

IFNAR1 signaling is associated with a decrease in IL-10R⁺ colonic APCs in <i>Salmonella</i>-infected mice. by Kailyn L. Stefan (4633705)

In-silico SHH KO results show a decrease in cytokines as comared to WT. by Shruti Marwaha (654096)

Absence of caveolin-1 decreases KCa2.3 endocytosis. by Yajuan Gao (309862)

“…</b> Knockout of caveolin-1 (Cav-1(−/−)) resulted in a significant decrease of KCa2.3 endocytosis, relative to WT MEFs (n = 3; *p<0.05). …”

CDH11 deficient mice have decreased expression of fibrotic mediators during development of liver fibrosis. by Mesias Pedroza (212574)

Lack of TLR signaling (MyD88^-/-) results in decreased levels of cytokines in the cornea. by Rose Y. Reins (2586106)

Phosphorylation of PFK2 is decreased in cardiomyocytes cultured in the absence of insulin and with diabetes. by Craig A. Eyster (9262632)

“…Scale bar 10μm. (B) Quantitation of mean fluorescence intensity (MFI) for pPFK2 are presented as whisker plots that encompass data from at least 18 cells, as detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0231806#pone.0231806.g001" target="_blank">Fig 1</a> (n = 3 biological replicates, and at least 6 cells per experiment). (*) IBMX or Isoproterenol treatment causes a significant increase (<i>p</i> < .001) compared to untreated WT cells; (†) Each WT (-ins) condition is significantly decreased (<i>p</i> < .001) compared to WT (+ins); (‡) all Akita conditions are significantly decreased (<i>p</i> < .001) compared to comparable WT conditions. …”

PKA signaling stimulated by the combination of isoproterenol and IBMX is decreased by the absence of insulin. by Craig A. Eyster (9262632)

“…Scale bar 10μm. (B) Quantitation of mean fluorescence intensity (MFI) for PKA-substrate are presented as whisker plots that encompass data from at least 18 cells, as detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0231806#pone.0231806.g001" target="_blank">Fig 1</a> (n = 3 biological replicates, and at least 6 cells per experiment). (*) Isoproterenol and IBMX treatment caused a significant increase (<i>p</i> < .001) compared to IBMX alone in all conditions. (‡) stimulated Akita and WT–ins conditions are significantly decreased compared to matching WT +ins conditions. …”

LPS-induced decrease in Sp1 DNA binding activity is associated with an increased NF-κB binding activity. by Xiaobing Ye (49295)

“…<p>Wild type (WT) mice were injected with saline (1 ml/kg, Con) or <i>Samonelia Enteritidis</i> LPS (10 mg/kg, i.p.). …”