SDS pancreas senescence is downstream of p53-dependent changes in protein synthesis. by Marina E. Tourlakis (751986)

“…<p><b>A,</b> Increased nuclei per acinar area (*<i>P</i> = 0.029, Wilcoxon Rank Sum Test) and <b>B,</b> decreased mean acinus diameter (**<i>P</i> = 0.0073 and <i>NS</i> = not significant, <i>P</i> = 0.142; unpaired, two-sided T-test) in <i>Sbds</i>^{<i>P–/R126T</i>}; <i>Trp53</i>^{<i>–/–</i>}pancreas at 30 days of age. …”

Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation-5 by Rebecca A Howard (78819)

Effect of adipose-derived stem cells (ASCs) on cytokine levels in bronchoalveolar lavage fluid. by Kyu-Sup Cho (770125)

“…ASCs (A) or ASCs derived from indoleamine 2, 3-dioxygenase (IDO)-knockout (KO) mice (B) treatment significantly decreased IL-4, IL-5, and IL-13, but increased IFN-γ, IL-10, and TGF-β in WT and IDO-KO asthmatic mice. …”

Image_2_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.tif by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_1_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_3_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Expression of AC5 and AC6 in WT and AMPKα2-/- mice. by Anne Garnier (130125)

Image1_Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.JPEG by Dan Sun (140898)

“…Furthermore, the treatment of lidocaine repressed tumor growth of ovarian cancer cells in vivo, in which the miR-382-5p expression was increased while SLC7A11 expression was decreased. …”

Root cell wall proteins with significant decreased in expression level under 50 µM Cu treatment identified by LC-ESI-MS/MS-based proteomics using SIEVE (<i>p</i><0.05 and fold chan... by Tingting Liu (267387)

“…</p><p>Root cell wall proteins with significant decreased in expression level under 50 µM Cu treatment identified by LC-ESI-MS/MS-based proteomics using SIEVE (<i>p</i><0.05 and fold chang >1.5).…”

<i>mMgat2</i> and <i>HuMgat2</i> mice become obese when fed a HFD. by J. Jose Corbalan (22439198)

Four-Dimensional Characterization of Thrombosis in a Live-Cell, Shear-Flow Assay: Development and Application to Xenotransplantation by Donald G. Harris (715907)

“…WT endothelia stimulated diffuse platelet adhesion (SA 65 ± 2%) and aggregation (FR 120 ± 1 a.u.), indicating high-grade thrombosis consistent with the rapid platelet activation and consumption seen in whole-organ lung xenotransplantation models. …”

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes by Shi-Ying Yuan (2937669)

“…Glucocorticoid-induced effects were attenuated by glucocorticoid-inducible kinase 1 (SGK1) inhibitor GSK650394, which also inhibited glucocorticoid induced phosphorylation of Forkhead box O3a (FOXO3a). Furthermore, glucocorticoid-induced down-regulation of GR was mimicked by the inhibition of AMPK and abolished by the AMPK activators or the histone deacetylase 5 (HDAC5) inhibitors. …”

IFN-γ producing T cells in the spleen increased in ICOS-KO mice but marginally decreased in ICOS-YF mice. by Xiaoling Gao (293089)

Hypoxic MSCs maintain stemness properties. by Rohini L. Kadle (4919335)

Effects of metformin on depressive behavior and expression of GR in prefrontal cortex of rat after chronic exposure to CORT. by Shi-Ying Yuan (2937669)

Expression analysis in strain B728a of three FecI-like ECF σ factor genes (<i>ecf5</i>, <i>ecf7</i>, and <i>ecf6</i>) and associated putative iron-responsive genes in low and high... by Poulami Basu Thakur (389600)

Image 5_Lyg1 deficiency aggravated LPS-induced chronic epididymal inflammation and sperm dysfunction in mouse.jpeg by XueXia Liu (13114949)

“…</p>Methods<p>Sixty-four wild-type (WT) and Lyg1 knockout (KO) mice were divided into four groups. …”

Source data for Figs 1E, 2E, 2G, 3B, 3D, 3H, 5D, 6B, 6E, 7B, 7E, S1A, S1B, S1C, S3B, S4, S5B, S5D, S6, S7B, S7D, S10B, S10C, S11B, S11C, S12B, and S12D. by Yongle Zhang (11355546)

Field evaluation of orange rust reaction and genotyping of molecular markers for the <i>G1</i> gene in a nuclear collection of 299 sugarcane accessions. by Gleicy Kelly Oliveira (19259604)

Model predicted OAE prevalence as a function of total mf prevalence compared with the original survey data obtained from Pion et al. [16]. by Samit Bhattacharyya (173222)