Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

Subjects:

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

Subjects:

TEM4 depletion decreases TEM4 mRNA and protein levels but no effect on spindle staining by the TEM4 antibody. by Diogjena Katerina Prifti (12988141)

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD4⁺ and CD8⁺ naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

“…B) CD43^-/- septic mice exhibited a decreased frequency of apoptotic naïve CD4⁺ T cells, defined as 7-AAD⁺ Annexin V⁺ CD44^LO CD62L^HI CD4⁺ cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”

Parasitological parameters of infected <i>EBi3</i>^<i>-/-</i> and WT mice. by Ester Alves Mota (8474316)

Functional categorization of <i>T. gondii</i> genes with increased or decreased expression in WT mice compared to <i>in vitro</i> in HFF cells. by Sini Skariah (130134)

“…Functional categorization of genes decreased <i>in vivo</i> in WT mice compared to <i>in vitro.…”

Fold change of TIL subsets in paired TNBCs (N = 12 pts including 10 prim-met, and 2 met-met specimens) using log2 ratio of metastatic versus primary TNBC (n = 10, ●) or second recu... by Ting-Fang He (5210948)

List of 186 genes that were increased more than 2-fold from control to galactose and decreased more than 1.5-fold from galactose to 2ME2. by Masaru Takashima (13851129)

Su(H) and RBPJ AOS variants decrease DNA binding. by Ellen K. Gagliani (11478756)

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

Mfsd2a KO mice have decreased liver TG with normal liver metabolism. by Justin H. Berger (297156)

Decreased osteoclasts invasion into bony defects of <i>db-/db-</i> mice. by Christoph Wallner (699861)

“…<p>(A) TRAP stainings of <i>db</i>^-/<i>db</i>^- and WT mice 7dpO revealed that osteoclasts invasion is decreased in <i>db</i>^-/<i>db</i>^- mice (arrows indicate TRAP-positive pixels) which could be confirmed by quantification of TRAP-positive pixel in the defect area (B). …”

Decrease of mitochondrial protein levels in human OPMD muscle biopsies. by Aymeric Chartier (713911)

<i>dnak14</i> mutant harbors a transposon insertion in the <i>dnaK</i> coding region and specifies a truncated DnaK protein. by Carissa Chan (18310140)

Loss of nsp14-ExoN activity decreases recombination frequency and alters recombination junction patterns across the genome. by Jennifer Gribble (10005444)

NRF2-mediated oxidative stress genes differentially expressed in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

MCP-1-deficiency decreased CD11c-expressing cells via impairing the production of ROS and decreased activation of PLCγ2, Akt, and ERK upon M-CSF stimulation in BMM. by Woon-Ki Kim (447798)

“…<p>BMMs from WT (open bar) and MCP-1-KO mice (oblique-lined bar) were incubated in the presence of M-CSF (30 ng/ml) with U73122 (10 µM), Akt inhibitor IV (0.3 µM), PD098059 (5 µM), DPI (50 nM), NAC (3 mM), or H₂O₂ (300 µM) for 4 d (A). *, <i>P</i><0.05; ***, <i>P</i><0.001 compared with vehicle-treated WT cells. …”

Fructooligosaccharides (FOS) or dead <i>L</i>. <i>salivarius</i> feeding decreased the intestinal bacterial overgrowth in STZ-DM mice. by Shu-Han Lin (4020353)

“…Total bacteria counts were significantly increased in STZ-DM mice and FOS or dead <i>L</i>. <i>salivarius</i> feeding decreased them. …”

Introduction of the D409V point mutation to the <i>GBA1</i> gene does not affect <i>GBA1</i> mRNA transcription or GCase protein translation. by Nicole K. Polinski (10947787)

WT host survival decreased with STAT6 KO-adapted <i>N</i>. <i>brasiliensis</i> infection. by Annabel A. Ferguson (17616286)