The influence of S226 phosphorylation on the interaction between SNX5 and SNX1 or SNX2. by Nao Itai (5954666)

Subjects:

PD-1-deficient CD45.2⁺ Tregs are more competitive than WT CD45.2⁺ Tregs in suppressing CD45.1⁺ conventional CD4 T cells following TCR stimulation <... by Liaoxun Lu (179293)

<i>Igfbp7</i>^−/− fibroblasts show decreased proliferation potential. by Sumanta Chatterjee (519822)

“…<p>To determine if Igfbp7 can affect cell proliferation in normal cells, fibroblasts were derived from the WT or <i>Igfbp7</i>^−/− embryos (WT MEF or KO MEF) and their expansion in tissue culture was examined. 5x10⁴-starting cells were placed in parallel cultures (day 0) and cell numbers on the indicated days were determined. …”

AA and DHA modulate phosphorylation of ERK1/2 in both FXR1-WT and KO macrophages. by Claude Lachance (201669)

“…<p>FXR1-WT (A and C) and FXR1-KO (B and D) macrophage cell lines (1×10⁶ cells) were untreated (Medium) or treated with AA (100 nM) or DHA (100 nM) for 21 h. …”

Sirt5 KO induces increased lysine succinylation and decreased ATP synthase activity in mouse heart mitochondria. by Mengli Zhang (6331172)

Reducing SIRT1 activity increases, and increasing SIRT1 expression decreases, mitochondrial enzymes in C₂C₁₂ myotubes and rat skeletal muscle. by Kazuhiko Higashida (351645)

“…Values are means ± SE for 6–10 experiments per group. <i>p</i><0.5 versus control. (B) Suppression of SIRT1 activity by expression of dominant-negative SIRT1 H355A in rat triceps muscle by electroporation resulted in increases in mitochondrial proteins. …”

The Rac1-64D mutation caused decreased Rac1 binding to PAK. by Fumin Chang (193521)

Responsiveness of WT and transgenic mice to complete carcinogenesis using B(a)P. by Jian Fu (41067)

“…<p>(A) Tumor multiplicity: SCC/mouse. Note decreased number of carcinomas in transgenic compared to WT animals (p<0.05). …”

Analysis of TFAM and Twinkle (TW) mice 8 weeks after arteriovenous fistula creation. by Masataka Ikeda (428186)

Epac activation increased MYPT phosphorylation via PLC/PKC. by Yoshiki Ohnuki (576298)

Subjects:

Effect of TFAM overexpression on mitochondrial DNA (mtDNA), mitoROS and mRNA expressions of matrix-metalloproteinase (MMP)-2 and MMP-9 in rat neonatal myocytes. by Masataka Ikeda (428186)

Epac activation increased RLC phosphorylation via PLC/PKC. by Yoshiki Ohnuki (576298)

Subjects:

Epac activation with 8CPT-AM induced RLC phosphorylation in the perfused hearts. by Yoshiki Ohnuki (576298)

Subjects:

Splicing assays of wt and mutant pre-mRNA in the absence and presence of wild-type StpA and mutant G126V-StpA by Rupert Grossberger (9105)

“…The reactions were performed in the presence of 5 mM MgCl, 0.5 mM GTP, 50 mM Tris–HCl (pH 7.3) and 0.4 mM spermidine (see Materials and Methods). () Splicing of the wt intron pre-RNA without added protein (full circles), with the addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). () Splicing of the C865U pre-RNA intron mutant without protein (full circles), with addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). …”

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation - Fig 5 by Femke van Diggelen (6499112)

Content of the intracellular Co²⁺; Ni²⁺ and Zn²⁺ in WT and NiCoZia mutant <i>Synechocystis</i> cells. by Gábor Patyi (11846776)

Cortactin knockdown results in decreased FA turnover. by Alok Tomar (139282)

(A) FACS measurements of mitochondrial membrane potentials in wt, P1b, and P0 cells exposed to MitoTracker by Lilli Winter (93188)

“…Values represent mean ± SEM. = 50 (wt), 47 (P1b), and 53 (P0) ROIs analyzed. (J) Cells expressing P1b EGFP were immunolabeled using antibodies to Drp-1 (a) and GFP (b). …”

Feeding and energy homeostasis regulation of <i>Snord116del</i> mice and their WT littermates. by Feng Ding (33360)

“…On HF diet, the daily intake of the deletion males (HD) was significantly lower than that of their WT littermates (HW) (<i>P</i><0.005). This was entirely due to decreased daytime intake. …”

Leucine injections reduces food intake and activates neurons in the ventral medial hypothalamus (VMH) in WT mice compared to <i>Slc6a15</i> KO mice. by Maria G. A. Hägglund (386708)

“…(F and G) Number of activated pS6 positive neurons ± SEM (c-Fos and pS6 positive cells) in brain regions after leucine or valine injections in <i>Slc6a15</i> KO and WT mice (n = 5–6/group). Valine induced significant reduction (p = 0.0096) of activated neurons in the mTOR pathway in VMH in WT mice. …”