X-Ray Psoralen Activated Cancer Therapy (X-PACT) - Fig 3 by Mark Oldham (2577727)

“…<p><b>A</b>: UV light activated psoralen was observed to reduce viable cells in 3 cell lines (data from Cell-Titer-Glo^® Luminescence Cell Viability Assay under UV light). …”

Generation and evaluation of a tamoxifen inducible system for huntingtin ablation in the adult mouse. by Paula Dietrich (340949)

“…Htt protein levels were independently evaluated and determined by the biopharmaceutical company BioFocus (A Galapagos Company). Cortices (left graph) and striata (right graph) from 3 month-old and 6 month-old C57BL/6 WT (3mo WT, 6mo WT accordingly), <i>Hdh</i>^{<i>flox/+</i>} (flox/+), <i>Hdh</i>^{<i>flox/-</i>} (flox/-), untreated cKO (cKO noTM) and cKO TM-treated at 3 months of age and harvested at 4 months (4mo cKO TM@3mo) or cKO TM-treated at 6 months of age and harvested at 7 months (7mo cKO TM @6mo) were analyzed. …”

Fig 3 - by Anne-Marie Rick (16324748)

“…<p><b>A-F.</b> SARS-CoV-2 anti-receptor binding domain (RBD) IgG and IgA geometric mean titer (GMT) in maternal and infant blood and milk before and after maternal COVID-19 booster vaccine (N = 45 pairs). …”

Model for distinct G-protein modulation of <i>I</i>_<i>Ba</i> and <i>I</i>_<i>Ca</i> mediated by Ca_v2.2. by Jessica R. Thomas (20691419)

“…<p>(A, B) Ca_v2.2 channels are potentiated by PIP2 binding and inhibited by Gβγ binding to the channel. …”

Model of the chromatin environment at the <i>HeT-A</i> promoter. by Rute Silva-Sousa (111978)

“…Subtle increase in JIL-1 and in euchromatinization of the <i>HeT-A</i> promoter. (D) In <i>Su(var)2-5</i> mutants: The lack of HP1a allows relaxation of the Z4 boundary causing a JIL-1 and Z4 spread along the HTT array and a relative decrease of these proteins inside the <i>HeT-A</i> promoter. …”

Data_Sheet_5_RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Prima... by Wenwen Si (5956190)

Gene expression and metabolite profiling of gibberellin biosynthesis during induction of somatic embryogenesis in <i>Medicago truncatula</i> Gaertn by Rafał Igielski (4281487)

“…In this study we show that during three week- long induction phase, when cells of leaf explants from non-embryogenic genotype (M9) and embryogenic variant (M9-10a) were forming the callus, all the bioactive gibberellins from non-13-hydroxylation (GA₄, GA₇) and 13-hydroxylation (GA₁, GA₅, GA₃, GA₆) pathways were present, but the contents of only a few of them differed between the tested lines. …”

MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification by Jianghua Liu (170107)

“…Here, we identified potential key miRNAs involved in vascular calcification <i>in vivo</i> and investigated the role of miR-32-5p (miR-32). According to microarray analysis, we observed increased expression of miR-125b, miR-30a, and miR-32 and decreased expression of miR-29a, miR-210, and miR-320 during the progression of vascularcalcification. …”

Table_1_Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and N... by Yee Qian Lee (10727655)

“…Increased caspase-3 activity and decreased bcl-2 concentration upon treatment indicate that MS13 induces apoptosis in these cells in a dose- and time-dependent manner. …”

Discovery of Potent, Selective, and Brain-Penetrant 1<i>H</i>‑Pyrazol-5-yl‑1<i>H</i>‑pyrrolo[2,3‑<i>b</i>]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors by Makoto Fushimi (1714441)

“…Scaffold hopping and lead optimization of <i>N</i>-(2,4-difluorobenzyl)-3-(1<i>H</i>-pyrazol-5-yl)­imidazo­[1,2-<i>b</i>]­pyridazin-6-amine <b>1</b> guided by a cocrystal structure of compound <b>1</b> bound to ALK resulted in the identification of (6-(1-(5-fluoropyridin-2-yl)­ethoxy)-1-(5-methyl-1<i>H</i>-pyrazol-3-yl)-1<i>H</i>-pyrrolo­[2,3-<i>b</i>]­pyridin-3-yl)­((2<i>S</i>)-2-methylmorpholin-4-yl)­methanone <b>13</b> as a highly potent, selective, and brain-penetrable compound. …”

Concentration-response curves to acetylcholine (ACh) before/after inhibition of EET formation by PPOH (10 μmol/l) or 17-ODYA (10 μmol/l) in phenylephrine (PE)-preconstricted renal... by Dandan Yin (4373071)

Image 5_Investigation of Tongqiao Huashuan Granules’ effect on hippocampal neuron autophagy in vascular dementia rats via the PI3K/Akt-mTOR signaling pathway using network pharmaco... by Xiaoqu Jiang (20912471)

PDE4 as a target in preterm labour-3 by Céline Méhats (29745)

NGF failed to induce persistent mechanical allodynia in Sp4+/- mice. SNI Sp4+/- mice developed mechanical hypersenstivity. by Kayla Sheehan (6406898)

File S1 - Budding Yeast Kinetochore Proteins, Chl4 and Ctf19, Are Required to Maintain SPB-Centromere Proximity during G1 and Late Anaphase by Soumitra Sau (594397)

“…</b> (A) Mean position of the KT (X_KT) measured from SPB is plotted against γ decreases for both WT and mutant cells. …”

Response of VP weight to a reference dose of 0 by William Owens (20777)

Galactose-1-phosphate uridyltransferase (GalT), an <i>in vivo</i>-induced antigen of <i>Actinobacillus pleuropneumoniae</i> serovar 5b strain L20, provided immunoprotection against... by Fei Zhang (85787)

“…Indirect enzyme-linked immunosorbent assay (ELISA) confirmed that GALT specific antibodies could not be induced by inactivated APP L20 or MS71 whole cell bacterin preparations. A recombinant fusion GALT protein derived from APP L20, however has proven to be an effective cross-protective antigen against APP sevorar 1 MS71 (50%, 4/8) and APP sevorar 5b L20 (75%, 6/8). …”

Osteonecrosis of the jaws: a review and update in etiology and treatment by Guilherme H. Ribeiro (4893625)

Immunofluorescence (IF) for Cx43 in hippocampus (A–D) and cerebellum (F–I). by Catarina Rapôso (5660521)

“…In the hippocampus, there was an intense decrease after 5 h of envenoming. E and J show the IF densitometric values for hippocampus and cerebellum, respectively (*p<0.05, **p<0.01 compared to control). …”

PEC 32 of Administrative Reform: A critical analysis by JOSÉ LUIS OREIRO (4985831)