Th2 cytokines and IgE were decreased in G-1-treated C57BL/6 mice compared to non-treated mice. by Masamichi Itoga (706167)

A model with two target-cell populations and viral competition in one of these populations matches <i>in vivo</i> data and predicts that R5 inhibitors accelerate AIDS onset. by Ariel D. Weinberger (169848)

“…(D) Time-dependency of X4 emergence as a function of CCR5 inhibitor efficacy (α-CCR5 efficacy) in the “competitive regime.” …”

PPARγ inhibition decreased effects of MAG incubation on PPARγ expression and insulin-stimulated signaling pathway in human umbilical vein endothelial cells. by Xiangyan Liang (431205)

Datasheet1_Quality of life, exercise capacity, cognition, and mental health of Chilean patients after COVID-19: an experience of a multidisciplinary rehabilitation program at a phy... by Valeria Paéz (17523354)

“…Moreover, physical therapy led to a reduction in neuropathic symptoms and pain, psychological therapy reduced anxiety and depression, and language therapy enhanced memory and speech (all p < 0.05). (3) Demographic and clinical history characteristics did not predict responses to rehabilitation. (4) A regression model for predicting changes in SF-36 total score, based on physical function, physical role, general health, and mental health, was established based on the data from study (p < 0.01, adjusted R² = 0.893). (5) Classification models for predicting dropouts achieved 68% accuracy, with key predictors of treatment adherence including diabetes, hypertension, and dyslipidemia, Tinetti balance, physical role, and vitality of SF36, and performance on the 6-minute walk test and 1-minute sit-to-stand.…”

Α-Difluoromethylornithine (DFMO) (2% per orally in drinking water) decreases polyamine levels in mammary fat pad tumors of MDA-MB-231 cells by Monica M Richert (63671)

Activation of the glucocorticoid receptor increases expression of the MKP-1/DUSP1 gene and decreases IL-1β-stimulated p38 MAPK phosphorylation. by Susan J. Burke (130329)

Effect of CSE Gene Deletion on the Phosphorylation of ERK1/2 and NF-kB p65 Activation in the Liver and Lung Following CLP Induced Sepsis. by Ravinder Reddy Gaddam (2939934)

“…<p>(A-B) Liver p-ERK1/2 expression. Phosphorylation of ERK1/2 (p-ERK1: P<0.01; p-ERK2: P<0.05) was increased following CLP induced sepsis in WT mice compared to sham operation controls. …”

Decreased glycosylated α-DG and laminin levels distal to the glial dome in <i>Large</i>^{<i>myd/myd</i>} mice. by Shigefumi Morioka (8893511)

Development of a Highly Efficient NIR-II Phototherapeutic Agent for Fluorescence Imaging-Guided Synergistic PTT/PDT/Chemotherapy of Colorectal Cancer by Ji Liu (110659)

Decreased expression levels and/or mislocalization of MYO6 and stereociliary taper-specific proteins in the hair cells of <i>ksv</i>/<i>ksv</i> mice. by Yuta Seki (4385833)

“…A similar decrease in the cuticular plates was observed in the utricle hair cells of <i>ksv/ksv</i> mice (E) and in IHCs stained with the anti-MYO6 (N-ter) antibody (F). …”

Expression of Fbln5 in targeted mice. by Kathleen Chin (275937)

“…</b> Hart’s stain of mid-vagina from <i>Fbln5</i>^f/f/SMA⁺⁺/Cre^- (<b>a. …”

Fast-slow decomposition of the model dynamics when the V0_V excitatory pathways are deleted. by Yaroslav I. Molkov (542831)

“…LF-RF<b>"</b> diagram in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004270#pcbi.1004270.g005" target="_blank">Fig 5B</a>, the left knees of the red nullclines are at higher <i>h</i>_<i>NaP</i> values than the left knee of the unperturbed (gray) <i>V</i>-nullcline (i.e. in the yellow area) thus making it possible for the LF to reach the yellow area during the active phase of the RF (i.e. by climbing up in the red band). …”

Tamoxifen injection induced efficient recombination within <i>Cdc25A</i> and <i>Cdc25B</i> loci. by Gwanghee Lee (271155)

“…Asterisk (*) indicates significantly different from WT, P  =  0.012 by Student's t-test. Note that <i>vB^f/−</i> mice are generated by crossing <i>Cdc25B</i> null mice <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015561#pone.0015561-Lincoln1" target="_blank">[26]</a> with <i>Cdc25B</i> conditional mice. …”

Gridding Triboelectric Nanogenerator for Raindrop Energy Harvesting by Bolang Cheng (11461820)

“…Under the impact of simulated raindrops from a shower at a flow rate of 0.137 mL/(cm²·s), the open-circuit voltage (<i>V</i>_oc) and the short-circuit current density (<i>J</i>_sc) of the G-TENG reach 400 V and 2.5 mA/m², respectively. …”

Gridding Triboelectric Nanogenerator for Raindrop Energy Harvesting by Bolang Cheng (11461820)

“…Under the impact of simulated raindrops from a shower at a flow rate of 0.137 mL/(cm²·s), the open-circuit voltage (<i>V</i>_oc) and the short-circuit current density (<i>J</i>_sc) of the G-TENG reach 400 V and 2.5 mA/m², respectively. …”

Clinical characteristics of the study population. by Hun Gi Lee (21526538)

“…The proportions of emergency surgeries (46.5%), ICU admissions (36.5%), and unfavorable outcomes (21.5%) decreased. …”

Supplementary Material for: Vitamin D₃ Treatment Decreases Frequencies of CD16-Positive and TNF-α-Secreting Monocytes in Asthmatic Patients by Grubczak K. (4152079)

“…Interestingly, we found that a combined treatment of 1,25-(OH)₂D₃ and GC allowed for a 5-fold reduction of the GC dose while maintaining their anti-inflammatory effects. …”

Deficiency of G1 regulators P53, P21and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest-2 by Sharon Sheahan (38663)

“…As for all experiments the -null hepatocytes were obtained by infection at the time of plating of the hepatocytes of corresponding genotypes with adenovirus expressing Cre recombinase. (1) all deficient hepatocytes respond less well to inhibition of proliferation by TGFβ than control cells and deficient has the strongest effect. (2) and deficiency, singly or together have a similar effect on inhibition of proliferation by TGFβ. (3) deletion significantly reduces TGFβ-induced cell cycle arrest regardless of and status (compare control with ; - with with - and with TRPL). (4) double deficiency in and further decreases hepatocytes responses to TGFβ in term of regulation of proliferation, independently of status. (5) by contrast the effect of TGFβ on hepatocytes deficient in both and is not significantly different to that of null cells, and this is independent of status. …”

Datasheet1_Polo-like kinase (PLK) 5, a new member of the PLK family, serves as a biomarker to indicate anabatic tumor burden and poor prognosis for resectable non-small cell lung c... by Kaichao Wang (14335569)

“…Objective<p>A review argues that polo-like kinase 5 (PLK5) may be linked to unfavorable prognosis in non-small cell lung cancer (NSCLC) patients, which contradicts the discoveries from The Human Protein Atlas database (derived from TCGA analysis). …”

Data_Sheet_1_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.docx by Dengpan Bu (369549)