Proposal for a diagnostic and therapeutic algorithm to manage rheumatic and musculoskeletal disorders persisting after acute chikungunya (CHIK) infection, with the following abbrev... by Emilie Javelle (700851)

“…⁵Immune-modulating biologic agents = rheumatologist prescription among anti-TNF (etanercept 25mg twice a week, infliximab 3–5 mg/kg/ 6–8 weeks, adalimumab 40 mg/ 2 weeks, golimumab 50mg/month), abatacept (inhibition of T-lymphocyte activation, 500–1000 mg/ 4 weeks), rituximab (depletion of B-lymphocytes, 1000 mg repeated at 2 weeks) and tocilizumab (inhibition of interleukin-6 receptor, 8 mg/ kg/ 2 weeks). …”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…In purple are EPSP percent changes for 4 recorded interneurons, which show heterogeneous changes during the UP state ranging from a 30% increase to a 65% decrease (mean: 26.5% decrease, standard deviation 50.0%; see gray bar at left of graph). …”

Basal ECD mutations have the greatest influence on activation. by Ákos Nemecz (356830)

“…The main subunit is shown in black with ribbon and cartoon representation, whereas the neighboring subunits are represented in white ribbon. Tables of the pH₅₀ and ΔpH₅₀ values are shown below with mean values ± standard deviation for evaluated mutants with recorded values noted in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2004470#pbio.2004470.s001" target="_blank">S1 Table</a>. …”

Telomere shortening culminates in tissue defects associated with aging. by Madalena C. Carneiro (102302)

“…<p>A) Representative haematoxylin and eosin-stained sections of gut, muscle and testis from WT and <i>tert</i>^<i>-/-</i> siblings. …”

Dopamine depletion increases intrinsic excitability of medium spiny neurons. by Karima Azdad (370732)

OCM impairment is involved in ethanol impact on DNA repair in the PFC. by Anna-Kate Fowler (625791)

“…<p>(A) Blood Hcy levels in WT and <i>Mthfr+/−</i> mice following acute or chronic 3- week (3 w) or 5-week (5 w) ethanol exposure. …”

Assessment of biomarker stability and reproducibility. by Jochen Neuhaus (152170)

“…The mean is marked with a bold line; standard deviation is highlighted in grey. …”

Lowering membrane negative charge further reduces tubulation ability for the D151N and R154Q mutants. by Tingting Wu (228837)

“…<p>A) Electron micrographs of liposomes (60% DOPC/20% DOPS/10% DOPE/10% PI(4,5)P₂) incubated with BIN1 N-BAR and the mutants. …”

Numerical Selectivity Evolves Rapidly in LIP by Jamie D Roitman (378823)

“…Responses are aligned to stimulus onset (dashed vertical line at zero) and shown for the full stimulus period (400 ms). Numerosity is indicated by line color. Inset: average response (mean ± SE) during the epoch 50–450 ms following stimulus onset.…”

Influence of Kar4 deletion on low affinity PRE sites. by Sandrine Pinheiro (21553774)

“…</b> Dynamics of nuclear enrichment of WT (solid lines) and <i>kar4∆</i> cells (dashed lines) with a synthetic promoter with 2 PREs spaced by 3 bp in tail-to-tail orientation and where one of the PRE sequences has been mutated to decrease the affinity to Ste12. …”

Diadinoxanthin (Ddx) concentration and de-epoxidation state (DES). by Benjamin Schellenberger Costa (461158)

“…Mean values of <i>aureo1a</i> cultures marked with asterisks (*) are significantly different to the WT culture of the same culturing condition according to one-way ANOVA followed by Holm-Sidak pair wise comparison against WT as control group (p<0.05). …”

Exemplar press-related channel. by David T. Bundy (7586414)

“…Mean firing rates show a complex task response with firing rates significantly (p<0.05) decreased around the lever press and 650 ms prior to the reach to the pellet and then significantly increased immediately prior to the reach to the pellet. …”

Loss of layer V pyramidal neurons of motor cortex. by Paolo d’Errico (494029)

“…(<b>C</b>) Nissl-stained brain sections illustrating reduced numbers of larger pyramidal neurons (red asterisks in the inset) in layer V of SMA mice <i>vs</i> WT controls. (<b>D</b>) Stereological counts of Nissl-stained brain sections revealing a significant 52% decrease (^**p<0.01, t-test) of pyramidal neuron density in layer V of P9 SMA <i>vs</i> WT mice. …”

The effect of extracellular glucose on the protein levels of ABCC11. by Yu Toyoda (2826734)

“…<p>(A and B) The decrease of the glycosylation and the protein levels of ABCC11 wild-type (WT) expressed in MDCKII cells cultured with a low-glucose medium. …”

Binding and activity of TM fusion proteins on mouse endothelial cells. by Colin F. Greineder (171596)

“…(d) Antibody blockade of EPCR results in a ∼50% decrease in APC generation by endogenous TM and anti-ICAM scFv/TM, but not anti-PECAM scFv/TM. …”

Incident light intensities and cellular parameters. by Benjamin Schellenberger Costa (461158)

“…Mean values of <i>aureo1a</i> cultures marked with asterisks (*) are significantly different to the WT culture of the same culturing condition according to one-way ANOVA followed by Holm-Sidak pair wise comparison against WT as control group (p<0.05). …”

MLL2 is not required for granulosa cell function. by Claudia V. Andreu-Vieyra (243666)

“…<i>Mll2^Amhr2</i> cKO granulosa cells show a significant decrease in the levels of <i>Mll2</i>, whereas <i>Mll2^F/</i>⁻ granulosa cells show the expected 50% decrease in <i>Mll2</i> levels (ANOVA test; * <i>p</i><0.05). …”

Effect of CCR5 mutations on entry of parental and resistant Env-pseudotyped viruses^*. by Reem Berro (68333)

“…A 50% decrease in entry efficiency was considered to be meaningful in this assay, so all values ≤50% are bolded. …”

Neurons from Kidins220^−/− mice showed normal post-tetanic potentiation and synaptic depression of evoked EPSCs. by Joachim Scholz-Starke (324807)

“…<p><b>A</b>) EPSCs recorded using a paired-pulse protocol (IPI = 50 ms) are presented before (left trace) and after (right trace) the application of a 1-s stimulation train at 40 Hz (middle trace). …”

Odor-evoked activity in the MOE and VNO is required for female sexual receptivity. by Eleanor J. Fraser (529109)

“…(D) Chemosensory control of female sexual receptivity. There was a significant effect on receptivity from both <i>Cnga2</i> and <i>Trpc2</i>, with no interaction between the two, resulting in a significant decrease in sexual receptivity in <i>Cnga2^-/-</i>, <i>Trpc2^-/-</i> double mutant females. …”