Deficiency of G1 regulators P53, P21and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest-2 by Sharon Sheahan (38663)

“…As for all experiments the -null hepatocytes were obtained by infection at the time of plating of the hepatocytes of corresponding genotypes with adenovirus expressing Cre recombinase. (1) all deficient hepatocytes respond less well to inhibition of proliferation by TGFβ than control cells and deficient has the strongest effect. (2) and deficiency, singly or together have a similar effect on inhibition of proliferation by TGFβ. (3) deletion significantly reduces TGFβ-induced cell cycle arrest regardless of and status (compare control with ; - with with - and with TRPL). (4) double deficiency in and further decreases hepatocytes responses to TGFβ in term of regulation of proliferation, independently of status. (5) by contrast the effect of TGFβ on hepatocytes deficient in both and is not significantly different to that of null cells, and this is independent of status. …”

Image1_Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential.pdf by X. Lin (3771379)

Data_Sheet_1_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.docx by Dengpan Bu (369549)

TCP24 interacts with the TGMV <i>CP</i> promoter <i>in vivo</i>. by Jacqueline Williams (3493745)

Data_Sheet_1_Fast Green FCF Alleviates Pain Hypersensitivity and Down-Regulates the Levels of Spinal P2X4 Expression and Pro-inflammatory Cytokines in a Rodent Inflammatory Pain Mo... by Fang Xu (138747)

“…We found that systemic administration of FGF reversed mechanical and thermal pain hypersensitivity evoked by CFA in a dose-dependent manner. FGF treatment decreased purinergic spinal P2X4 expression in the spinal cord of CFA-inflamed mice. …”

DataSheet_1_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.docx by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

CD28 blockade with mPEG PV1-Fab’ prevents T_H1 cell expansion after antigen re-encounter. by Pedro Henrique Papotto (791904)

Datasheet1_Quality of life, exercise capacity, cognition, and mental health of Chilean patients after COVID-19: an experience of a multidisciplinary rehabilitation program at a phy... by Valeria Paéz (17523354)

“…Moreover, physical therapy led to a reduction in neuropathic symptoms and pain, psychological therapy reduced anxiety and depression, and language therapy enhanced memory and speech (all p < 0.05). (3) Demographic and clinical history characteristics did not predict responses to rehabilitation. (4) A regression model for predicting changes in SF-36 total score, based on physical function, physical role, general health, and mental health, was established based on the data from study (p < 0.01, adjusted R² = 0.893). (5) Classification models for predicting dropouts achieved 68% accuracy, with key predictors of treatment adherence including diabetes, hypertension, and dyslipidemia, Tinetti balance, physical role, and vitality of SF36, and performance on the 6-minute walk test and 1-minute sit-to-stand.…”

EDA-DATA by QiMin Zhou (17299183)

Database of digitized Kato-Katz slide samples from the 6 positive patients. by Elena Dacal (4805964)

Contribution of TAT System Translocated PhoX to <em>Campylobacter jejuni</em> Phosphate Metabolism and Resilience to Environmental Stresses by Mary Drozd (199923)

“…Further, the Δ<em>phoX</em> mutant produced increased biofilm that can be rescued with 1 mM inorganic phosphate. …”

Time series trends showing predicted six-month retention for cohorts enrolled in each month from January 2015 through December 2018 comparing pre-UTT (2015–2016) and UTT (2017–2018... by Levicatus Mugenyi (6393749)

Oncostatin M Mediates STAT3-Dependent Intestinal Epithelial Restitution via Increased Cell Proliferation, Decreased Apoptosis and Upregulation of SERPIN Family Members by Florian Beigel (174724)

mPEG PV1-Fab’ dampens IFN-γ production by CD4⁺ T lymphocytes. by Pedro Henrique Papotto (791904)

S1 Table - by Penny A. Rudd (10298691)

Quantification of apoptosis and necrosis by flow cytometry in CsA-treated HRE cells: Effect of GADD45G knockdown. by Gyu-Tae Shin (5819249)

Table_5_A metabolome genome-wide association study implicates histidine N-pi-methyltransferase as a key enzyme in N-methylhistidine biosynthesis in Arabidopsis thaliana.xlsx by Kai Uchida (16076942)

Datasheet1_Polo-like kinase (PLK) 5, a new member of the PLK family, serves as a biomarker to indicate anabatic tumor burden and poor prognosis for resectable non-small cell lung c... by Kaichao Wang (14335569)

“…Objective<p>A review argues that polo-like kinase 5 (PLK5) may be linked to unfavorable prognosis in non-small cell lung cancer (NSCLC) patients, which contradicts the discoveries from The Human Protein Atlas database (derived from TCGA analysis). …”

DataSheet_5_A Novel Image Analysis Approach Reveals a Role for Complement Receptors 1 and 2 in Follicular Dendritic Cell Organization in Germinal Centers.pdf by Jessica C. Anania (5644553)

“…Mice were immunized with SRBC i.v. and spleen and serum samples harvested at various time points. …”

Data_Sheet_1_The role of booster vaccination in decreasing COVID-19 age-adjusted case fatality rate: Evidence from 32 countries.docx by Cui Zhou (1388874)