Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making by Almutairi, Adel F.

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Percutaneous Aspiration Irrigation Drainage Technique in the Management of Septic Arthritis in Children by Hayek, Toni

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Dietary protein level alters gentamicin-induced nephrotoxicity in rats by Zeeni, N.

“…Two studies have been conducted (1) to assess the protein level of a diet that would give the best renal outcome with gentamicin administration, and (2) to get a better idea about the rhythms of food ingestion associated with the different protein levels. …”
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Palladin Regulates Invadopodia Formation in Glioblastoma by Abi Khalil, Elie

“…More recently, palladin has been shown to alter actin dynamics in podocytes as well as replace the Arp2/3 complex during Listeria infections, contributing to the assembly of actin-based structures. …”
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The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic by Shireen Suliman (13554986)

“…Graduate medical education leaders should adopt measures to monitor their use during ward rounds as they can negatively impact trainees’ education, reduce interaction with patients, increase the risk of infection, and breach patient confidentiality.</p><h2>Other Information</h2><p dir="ltr">Published in: Advances in Medical Education and Practice<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/amep.s395501" target="_blank">https://dx.doi.org/10.2147/amep.s395501</a></p>…”

Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes by Abi-Gerges, Aniella

“…This channel is gated by cAMP and thus allow to follow cAMP dynamics by recording the associated cationic current (ICNG) with the whole cell patch clamp technique 24 h after infection. Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …”
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Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update by Maria K. Smatti (4675852)

“…Among all the EBV genes, most of the recent investigations focused on studying the LMP-1 oncogene because of its high degree of polymorphism and association with tumorigenic activity. There are two main EBV genotypes, Type 1 and 2, distinguished by the differences in the EBNA-2 gene. …”

Magnesium-reinforced PMMA composite scaffolds: Synthesis, characterization, and 3D printing <i>via</i> stereolithography by Ambreen Afridi (22224310)

“…Additionally, Mg can potentially regenerate skin tissues and inhibit bacterial infections. Mg ions are crucial for wound healing because they repair the skin barrier and facilitate blood coagulation. …”

Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study by Husham Abdelrahman (768893)

“…There was a significant decrease in the trend of geriatric trauma over the years. …”

Elastic stable intramedullary nailing of tibial shaft fractures in children by El Hayek, Toni

“…As early as day 30, all patients had normal knee mobility and symmetrical foot progress angle. At 2-year follow-up, frontal angulation and leg length discrepancy had decreased and affected 2% of patients. …”
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Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy by Moayyad Shawaqfah (17280637)

“…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …”

Leishmania major by Daher, Costantine F.

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Raising awareness of menopause in Iran by Nature Research (16552612)

“…It can also come with an increased risk for physical and mental health problems, including depression, vaginal infection, and weight gain. …”

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…FindingsGlobal new HIV infections decreased by 21·9% (95% UI 13·1–28·8) between 2010 and 2021, from 2·11 million (2·02–2·25) in 2010 to 1·65 million (1·48–1·82) in 2021. …”
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation by Salman, Zeina

“…Quantitative PCR revealed that FliC stimulation upregulated miR-222-5p and miR-21-3p expression within 2 hours of treatment. Functional assays revealed that miR-222-5p overexpression led to a significant increased expression of key pro-inflammatory cytokines, including IL-8 and TNF-α, while knockdown of these miRNAs resulted in their decreased expression. …”
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Comparative effectiveness of one versus two doses of COVID-19 vaccines in Qatar: Evidence of converging protection over time by Hiam Chemaitelly (439114)

“…Similar trends were observed for mRNA-1273 and ChAdOx1 nCoV-19, with mRNA-1273 reaching two-dose levels of effectiveness as early as month 2. In contrast to the gradual buildup of protection against infection, single-dose effectiveness against severe, critical, or fatal COVID-19 increased rapidly for all three vaccines, exceeding 85 % by day 21 and closely matching the protection achieved after two doses.…”

Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan by Ali Ahmed (2567584)

“…ART has significantly increased the life expectancy of people living with HIV/AIDS (PLWHA). …”

A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge by Salim Al Lahham (16515333)

“…</p><h3>Results</h3><p dir="ltr">None of our patients had distal necrosis, infection, or dehiscence, and all had protective sensation in the flap. …”

Carotid artery revascularization through a radiated field by Lesèche, Guy

“…In a prospective study, late (>70%) carotid artery stenosis was found in 11.7% of 240 patients who had undergone cervical irradiation.6 The chronic effects of radiation therapy lead to decreased vascularity and increased fibrosis, which in turn lead to risk for tissue necrosis, infection, and ulceration. …”
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Platelet Protein-Related Abnormalities in Response to Acute Hypoglycemia in Type 2 Diabetes by Abu Saleh Md Moin (6189512)

“…<h3>Introduction </h3><p dir="ltr">Patients with severe COVID-19 infections have coagulation abnormalities indicative of a hypercoagulable state, with thromboembolic complications and increased mortality. …”