يعرض 1 - 20 نتائج من 202 نتيجة بحث عن '(( k nn decrease ) OR ((( 5 we decrease ) OR ( _ text decrease ))))', وقت الاستعلام: 0.16s تنقيح النتائج
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…By elucidating a mechanistic basis for the increased affinity of the N501Y mutant S1-RBD for ACE2, we believe that the results presented here will aid in developing therapeutic strategies against SARS-CoV-2 including designing of therapeutic agents targeting the ACE2-S1-RBD interaction.…"
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    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

    منشور في 2023
    "…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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    Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

    منشور في 2023
    "…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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    Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

    منشور في 2025
    "…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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    Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

    منشور في 2019
    "…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"
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    BRET-based biosensors for SARS-CoV-2 oligonucleotide detection حسب Asfia Sultana (19170880)

    منشور في 2024
    "…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …"
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    Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic حسب Turki, O.

    منشور في 2023
    "…We report the impact of dysprosium (Dy, with y = 0.01, 0.02, 0.05 and 0.08) substitution in (Na0.5 Bi0.5)0.94 Ba0.06TiO3 (NBT-6BT) lead-free ceramics. …"
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    Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature حسب Henry C. Ezechukwu (13253406)

    منشور في 2022
    "…To date, the vertical transmission of SARS-CoV-2 during pregnancy remains controversial. We briefly report recent findings of placental response to SARS-CoV-2 infection and updates on vertical transmission. …"
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    Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis حسب Maria K. Smatti (4675852)

    منشور في 2020
    "…</p><h3>Methods</h3><p dir="ltr">We extracted the list of SNPs that could potentially modulate SARS-CoV-2 from the genome wide association studies (GWAS) on SARS-CoV-1 and other viruses. …"
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    Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans حسب Engin Baturcam (309036)

    منشور في 2014
    "…In the present study, we investigated for the first time the effect of physical exercise on the expression of RANTES and CCR5 in obese humans. …"
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    A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor حسب Anupriya M. Geethakumari (17052375)

    منشور في 2022
    "…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M<sup>pro</sup> activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M<sup>pro</sup> and functional genomics application to determine the effect of sequence variation in M<sup>pro</sup>.…"
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    Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... حسب Katherine R Paulson (8674293)

    منشور في 2021
    "…</p><p><br></p><h3>Methods</h3><p dir="ltr">We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (U5MR). …"
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    Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform حسب Angelin Mary Philip (21547421)

    منشور في 2024
    "…Specifically, we functionalized bilayers with the fluorescently labelled S1-RBD and monitored the interaction of ACE2 expressing A549 cells. …"
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    Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

    منشور في 2025
    "…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. …"
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    Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment حسب Christos Fountoukis (4722963)

    منشور في 2022
    "…The overall forecast error decreased from –51% to 8% for PM2.5 and from –88% to 20% for NOx while a significant improvement was observed in the diurnal profile of predicted ozone. …"
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    The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

    منشور في 2023
    "…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. …"