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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
Published 2021“…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…The upregulation of 40S ribosomal protein S9 (3-fold), 40S ribosomal protein S15 (4.2-fold), 40S ribosomal protein S18 (2.5-fold), and 60S ribosomal protein L22 (4.4-fold) implied the induction of translation machinery. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Non-diabetic ketoacidosis secondary to primary hyperthyroidism
Published 2022“…One infrequent complication of hyperthyroidism is non-diabetic ketoacidosis (NDKA). To the best of our knowledge, our case is the third report of NDKA related to thyrotoxicosis.…”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
Published 2020“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…”
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eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …”
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
Published 2024“…This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …”
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
Published 2024“…<p>This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …”
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Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…CPHN cells represent a non-replicative pool of endocrine precursor cells, a proportion of which are likely fated to become beta-cells.…”
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Determinants of Non-Performing Loans in the State of Qatar With Special References to Small and Medium Enterprises
Published 2024“…<p dir="ltr">This research examines borrower-specific and bank-specific factors affecting Qatar's non-performing loans (NPLs). This is done by investigating the factors influencing SMEs' failure to meet their financial obligations with banks in Qatar. …”
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Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene
Published 2023“…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…”
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…Less effective cuttings transportation (i.e lower CTR) was observed when the hole angle deviated from the vertical. …”
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Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance
Published 2024“…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …”
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Effective non-intrusive load monitoring of buildings based on a novel multi-descriptor fusion with dimensionality reduction
Published 2020“…<p dir="ltr">Recently, a growing interest has been dedicated towards developing and implementing low-cost energy efficiency solutions in buildings. Accordingly, non-intrusive load monitoring has been investigated in various academic and industrial projects for capturing device-specific consumption footprints without any additional hardware installation. …”
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The impact of climatic conditions on the carcinogenic and non-carcinogenic risk of BTEX compounds: A systematic review and meta-analysis
Published 2024“…This systematic review and meta-analysis study aimed to investigate the impact of climatic conditions on carcinogenic and non-carcinogenic risk value changes during exposure to BTEX compounds. …”
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Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students
Published 2022“…The AI of the CMJ was 15% higher, and that of the YBT was 7% higher in non-obese students than obese students. These findings contribute to the knowledge of the local community and the emerging body of literature on motor skills and competence related to weight in this population.…”
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
Published 2022“…Significant differences included various frequency domain and nonlinear HRV parameters, particularly between first and fourth HN quintiles with p values < 0.001 for recurrence plot analysis (RPA), detrended fluctuation analysis (DFA) a1 and Poincaré plot ratio SD1/SD2. The results revealed non-monotonic relationships between measures of HRV and HN concentration. …”
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