Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals by Abi-Gerges, Aniella

“…The inotropic response to maximal β-adrenergic stimulation was reduced by ≈54% in isolated hypertrophied hearts, along with a ≈32% decrease in subsarcolemmal cAMP levels in hypertrophied myocytes. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex by Wesam S. Ahmed (10170053)

“…The MOV files 5 to 8 are now removed from the <b>Supplementary Material</b>.</p><p dir="ltr">In the published article, there was also an error in the “<b>Materials and Methods</b>” section, sub-section “<i>ACE2-S1-RBD Molecular Dynamics Simulation Trajectory Analysis</i>”, <b>paragraph 1</b>. …”

Solubilization of Protein Aggregates by the Acid Stress Chaperones HdeA and HdeB by Malki, Abderrahim

“…We observed a decrease in the size of protein aggregates in the presence of HdeA and HdeB, from very high molecular mass aggregates to 100–5000-kDa species. …”
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Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats by Kanbar, Roy

“…Photostimulation increased BP (4 mmHg) and renal sympathetic nerve discharge (43%) while decreasing heart rate (15 bpm). Conclusions: Photostimulation of ChR2-transfected RVLM Phox2b neurons produces a vigorous stimulation of breathing accompanied by a small sympathetically mediated increase in BP. …”
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Using B₄C Nanoparticles to Enhance Thermal and Mechanical Response of Aluminum by Fareeha Ubaid (14151129)

“…It was observed that the density decreased and porosity increased with an increase in B4C content in aluminum matrix. …”

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”

Correlating process parameters to thrust forces and torque in the friction stir processing of AZ31B by Ammouri, Ali

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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…”

mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation by Georgess, Dan

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A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

“…Brain-derived neurotrophic factor (BDNF) and its TrkB receptor play critical roles in the synaptic activity and plasticity of mature neurons and enhance adult neurogenesis. …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Doua Abdelrahman (17280667)

“…Results: Only 1.4% (70/5026) of the samples had detectible B19V DNA in their blood. B19V DNA prevalence statistically decreased with age (p = 0.03). …”

Successful Use of Intravenous B-blocker Therapy in Cardiogenic Shock Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Case Series by Alaa Rahhal (14150403)

“…<p dir="ltr">Tachycardia in cardiogenic shock (CS) might reduce the cardiac output (CO) by decreasing the ventricular filling time. Nevertheless, heart rate (HR) control with agents that possess negative inotropy might decrease the CO. …”

Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002) by Berberi, Rania

“…The studies reported here evaluated the effects of acute and chronic 3% alcohol intake from either beer or whisky in drinking water upon blood lipids, lipoproteins and apolipoprotein B (apo B) profiles in the fasted and postprandial states. …”
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

“…We estimated <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/chronic-hepatitis-b" target="_blank">chronic HBV infection</a> and the burden of HBV-related diseases, defined as an aggregate of <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cirrhosis" target="_blank">cirrhosis</a> due to hepatitis B, liver cancer due to hepatitis B, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/acute-hepatitis-b" target="_blank">acute hepatitis B.…”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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The effect of IL-1RA and IL-13 on cutaneous leishmaniasis in BALB/C mice as to hyperalgesia and the levels of IL-1b and IL-6. (c2005) by Hamdan, Hamdan Ghazi

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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…We find that the most potent peptide inhibitor disrupts the direct interaction between the C-terminal region of α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B), a component of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III). …”