Search alternatives:
process optimization » model optimization (Expand Search)
linear optimization » lead optimization (Expand Search), after optimization (Expand Search)
library based » laboratory based (Expand Search)
based process » based processes (Expand Search), based probes (Expand Search), based proteins (Expand Search)
binary data » primary data (Expand Search), dietary data (Expand Search)
data linear » data linkage (Expand Search)
process optimization » model optimization (Expand Search)
linear optimization » lead optimization (Expand Search), after optimization (Expand Search)
library based » laboratory based (Expand Search)
based process » based processes (Expand Search), based probes (Expand Search), based proteins (Expand Search)
binary data » primary data (Expand Search), dietary data (Expand Search)
data linear » data linkage (Expand Search)
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<i>De Novo</i> Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization
Published 2020“…In the present study, we conceived a novel pair-based multiobjective approach implemented in an adapted SMILES generative algorithm based on recurrent neural networks for the automated <i>de novo</i> design of new molecules whose overall features are optimized by finding the best trade-offs among relevant physicochemical properties (MW, logP, HBA, HBD) and additional similarity-based constraints biasing specific biological targets. …”
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An optimal solution for the HFS instance.
Published 2025“…In recent years, due to the advantages of nonlinear access and fully parallel processing, the probe machine has shown powerful computing capabilities and promising applications in solving various combinatorial optimization problems. …”
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Improved support vector machine classification algorithm based on adaptive feature weight updating in the Hadoop cluster environment
Published 2019“…This result reflects the effectiveness of the algorithm, which provides a basis for the effective analysis and processing of image big data.…”
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Comparison based on hard instances from [79].
Published 2025“…In recent years, due to the advantages of nonlinear access and fully parallel processing, the probe machine has shown powerful computing capabilities and promising applications in solving various combinatorial optimization problems. …”
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