Showing 1 - 20 results of 26 for search '(( library based protein classification algorithm ) OR ( binary 3d codon optimization algorithm ))', query time: 0.54s Refine Results
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    Systematically Scrutinizing the Impact of Substitution Sites on Thermostability and Detergent Tolerance for <i>Bacillus subtilis</i> Lipase A by Christina Nutschel (4468498)

    Published 2020
    “…Our results provide systematic and unbiased reference data at unprecedented scale for a biotechnologically important protein, identify consistently defined hot spot types for evaluating the performance of data-driven protein-engineering approaches, and show that the rigidity theory and ensemble-based approach Constraint Network Analysis yields hot spot predictions with an up to ninefold gain in precision over random classification.…”
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