Search alternatives:
largest decrease » larger decrease (Expand Search)
reader decrease » greater decrease (Expand Search), teer decrease (Expand Search), greatest decrease (Expand Search)
marked decrease » marked increase (Expand Search)
largest decrease » larger decrease (Expand Search)
reader decrease » greater decrease (Expand Search), teer decrease (Expand Search), greatest decrease (Expand Search)
marked decrease » marked increase (Expand Search)
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The m6A reader YTHDF2 protects vascular smooth muscle cells against the osteogenic differentiation through targeting Runx2
Published 2025“…The M6A-modified mRNA degradation process is mediated by the reader YTHDF2 in an m6A-dependent manner. …”
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A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid
Published 2025“…Metabolomics revealed that P. goldsteinii increases 1,4-methylimidazoleacetic acid (MIAA), a metabolite linked to decreased body weight in animal models. Mechanistically, we show that MIAA inhibits the expression of the demethylase FTO, leading to increased m6A modifications on Slc2a4 mRNA via the reader protein YTHDC1. …”
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Data Sheet 1_Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study.docx
Published 2025“…GSVA showed that the two types of m6a regulation, namely m6a-readers and m6a-writers, were generally suppressed in DKD patients. …”
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S1 File -
Published 2025“…Following the overexpression of miRNA 221 in myocardium, there was a marked alleviation of myocardial injury and cardiomyocyte apoptosis and necrosis, significant enhancement of left ventricular systolic function, and marked decrease in the levels of PLB, p-PLB (Ser16), p-PLB (Thr17), caspase 3 and Cyt C, as well as a significant decrease in total calcium levels in myocardium.…”
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