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    Epithelial cell-size dysregulation is also found in mouse tumors and may proceed with loss of tissue organization and upregulation of transcription. by Clifford W. Sandlin (13919632)

    Published 2022
    “…Stage II involves more mixed stroma/tumor regions and disorganization, leading to sparse cells and increased cell size dysregulation. Late stage (III-IV) cancers are dominated by adaptation towards maximal cell division rate, evolution of immune resistance, and also loss of cytokeratin staining. …”
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