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<b>Supporting data for manuscript</b> "<b>Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins</b>"
Published 2025“…<p dir="ltr">The CSV file 'Eyreetal_DrainingVein_SourceData' contains the averaged time series traces and extracted metrics from individual experiments used across Figures 1-5 in the manuscript "Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins". The following acronyms included in the CSV file are defined as follows: Hbt is total hemoglobin, Art is artery region, DV is draining vein region, WV is whisker vein region, SEM is standard error mean, TS is time series, max peak is maximum peak, min peak is minima, AUC is area under the curve, WT is wild-type, AD is Alzheimer's disease, ATH is atherosclerosis and MIX is mixed AD/atherosclerosis. …”
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Validation of genetic markers for risk of OA or knee OA for decrease in minJSW.
Published 2025“…<p><b>(A)</b> Manhattan plot of minJSW decrease at 24 months. …”
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B2 decreases glycolytic intermediates in cells.
Published 2025“…<p>A-498 cells were treated with B2 or PFK158 for 60 min and then metabolites were extracted for LC/MS analysis. …”
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Mechlorethamine gel causes epithelium thinning, epithelium-stroma separation, and decreased total stroma cell count.
Published 2025“…<p>A) Epithelium thickness decreased, and B) the percentage of epithelium-stroma separation increased after NM exposure. …”
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PBP1 depletion results in a population of cells with decreased RADA fluorescence.
Published 2025“…<p><b>(A)</b><i>C. difficile</i> harboring the <i>pbp1</i>-KD cassette and pRPF185-P<sub>tet</sub>-<i>gusA</i> was cultured in the presence and absence of xylose and/or aTc per the scheme indicated in Fig 2C, and cells were labeled with RADA for 10 min, fixed, and imaged by fluorescence microscopy. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
Published 2024“…Mechanistically, compound <b>E35</b> markedly decreased the expression of Skp2, as well as increased the expression of its substrates p21 and p27. …”