Search alternatives:
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
026 decrease » a decrease (Expand Search)
nn decrease » a decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
n 026 » n 26 (Expand Search), n 526 (Expand Search)
50 nn » 50 ns (Expand Search), 50 ng (Expand Search), 50 n (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
026 decrease » a decrease (Expand Search)
nn decrease » a decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
n 026 » n 26 (Expand Search), n 526 (Expand Search)
50 nn » 50 ns (Expand Search), 50 ng (Expand Search), 50 n (Expand Search)
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X‑Ray Conformation and Structure–Activity Relationships of MA026, a Reversible Tight Junction Opener
Published 2023“…We reported that (1) TJ-opening activity is dependent on the amino acid sequence order at Glu10-Leu11; (2) an epimer at the C3 position of the <i>N</i>-terminal acyl tail decreased the TJ-opening activity; and (3) the epimers D-Leu1/L-Gln6 and L-Leu1/D-Gln6 showed more potent TJ-opening activity than natural MA026, although no systematic structure–activity relationship (SAR) study was conducted. …”