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At lower concentrations, METH decreases LTP.
Published 2010“…At 0.1 µM METH, LTP was 1.58±.08 [<i>n</i> = 13(5)] (Fig. 1B); at 1 µM METH, LTP was 1.50±.07 [<i>n</i> = 13(7)] (Fig. 1C); at 10 µM METH, LTP was 1.58±.07 [<i>n</i> = 14(8)] (Fig. 1D); at 30 µM METH, LTP was 1.37±.06 [<i>n</i> = 15(4)] (Fig. 1E); and at 60 µM METH, LTP was 1.32±.24 [<i>n</i> = 4(2)] (Fig. 1E). …”
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TIG3 decreases cell survival.
Published 2013“…At 0, 24, 48, and 72 h post-infection, cells were counted and lysates prepared. <b>A</b> TIG3 expression decreases cell number. Values are mean ± SEM, n = 3. …”
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Vasopressin decreases EPSPs in CA2 after LTP induction.
Published 2013“…<p>A: Top: typical recordings of the combined EPSP/IPSP evoked by stimulation of LIII entorhinal fibers (EC LIII) and recorded in CA2 pyramidal neurons (inset). …”
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The expression of genes related to mitochondria was decreased in Pgam2 mice.
Published 2013“…Peroxisome proliferator-activated receptor α (PPARα), peroxisome proliferator-activated receptor δ (PPARδ), estrogen related receptor α (ERRα), mitochondrial transcription factor A (Tfam), carnitine palmitoyltransferase 1b (CPT-1b), isocitrate dehydrogenase 3 α (IDH3α), oxoglutarate dehydrogenase (OgDh), succinyl-CoA synthetase α (SCS), mitochondrially encoded NADH dehydrogenase 4 (ND4), alpha-subcomplex 9 of complex I (α-s9), mitochondrial succinate dehydrogenase iron-sulfur subunit (SDHB), iron-sulfur protein (Fe-S), cytochrome b (Cyt-b), cytochrome c (Cyt-c), cytochrome c oxidase subunit VIIa (COX7a), uncoupling protein 2 (UCP2), uncoupling protein 3 (UCP3), and manganese superoxide dismutase (Mn-SOD) levels were decreased in Pgam2 mice. …”
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