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Ethanol withdrawal (EW) decreases GluN2A subunit levels.
Published 2013“…<p>NMDA subunit protein levels measured by Western blot analysis: GluN2A levels (B) decrease during ethanol withdrawal, whereas the levels of GluN1 (A) and GluN2B (C) remain unaltered. …”
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Decreasing NR1 and NR2A gene expression in 5-, 14- and 21-day groups.
Published 2017“…The expression of NR1 <b>(A)</b> and NR2A <b>(B)</b> in the hippocampus of each MMPM group showed a significant decrease compared with the control group.…”
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DTG mice have significantly decreased troponin I phosphorylation and Serca2 expression.
Published 2013“…<p>(A) Representative Western blots depicting no changes in the expression of phosphorylated protein kinase A (P-PKA) and decreased expression of phosphorylated troponin I (P-TnI) and Serca2. ß-tubulin was used as a loading control. …”
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Beta-catenin signaling is decreased in intermediate progenitor cells.
Published 2010“…Scale bars are 50 µm. * * = P<0.001, t test, two-tailed. (<b>C</b>) To further quantify signaling differences between Tbr2+ and Tbr2- cells, dorsolateral neocortices from E13.5 Eomes::GFP embryos (n = 3) were FACS sorted for GFP+ and GFP- cells (see cartoon). mRNA from these cells was isolated and reverse transcribed into cDNA for real-time PCR analysis. …”
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GluN2A(D731N) decreases current amplitudes and shortens synaptic-like response time course.
Published 2017Subjects: -
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(R+S) and (R)-albuterol decrease NF-κB activity
Published 2011“…</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2253534.</p><p></p> A NF-κB luciferase reporter construct (pGL2) was cotransfected with a β-galactosidase (pGK) reporter construct by electroporation into T (EL4) cells. …”
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