Showing 1 - 5 results of 5 for search '(( primary protein design optimization algorithm ) OR ( binary task codon optimization algorithm ))', query time: 0.51s Refine Results
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    DataSheet1_Quantum-assisted fragment-based automated structure generator (QFASG) for small molecule design: an in vitro study.docx by Sergei Evteev (18294157)

    Published 2024
    “…</p><p>Results: New low-micromolar inhibitors of CAMKK2 and ATM were designed using the algorithm.</p><p>Discussion: These findings highlight the algorithm’s potential in designing primary hits for further optimization and showcase the capabilities of QFASG as an effective tool in this field.…”
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    Supplementary Material for: The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Study: Trial Design and Baseline Characteristics by Wong M.G. (11640685)

    Published 2021
    “…The mean age of randomized participants was 38, 39% were female, mean eGFR at randomization was 62.7 mL/min/1.73 m<sup>2</sup>, and mean 24-h urine protein 2.54 g. The primary endpoint is a composite of 40% eGFR decline from baseline or kidney failure (dialysis, transplantation, or death due to kidney disease), and participants will be followed until the primary outcome has been observed in at least 160 randomized participants. …”