Transcriptomics-Driven Discovery of New Meroterpenoid Rhynchospenes Involved in the Virulence of the Barley Pathogen <i>Rhynchosporium commune</i> حسب Reynaldi Darma (20713741)

"…<i>Rhynchosporium commune</i>, the causal agent of barley scald disease, poses a major threat to global barley production. Despite its significant impact, the molecular mechanisms underlying <i>R. commune</i>’s infection process remain largely unexplored. …"

Table1_Indole-3-acetic acid treatment promotes postharvest kiwifruit softening by regulating starch and cell wall metabolism.docx حسب Wenhao Guan (3758572)

"…<p>The softening process of postharvest kiwifruit is a critical aspect of fruit quality that has been extensively studied. …"

Weight gain was associated with worsening glycemia and cardiovascular and kidney outcomes in type 2 diabetes patients independent of diabetes medication in the GRADE Randomized Con... حسب Deborah J. Wexler (492527)

"…Thereafter, weight decreased in all groups. Weight gain within the first six months was associated with increased risk of HbA1c>7.5%, with modest differences by treatment, and with subsequent CVD (HR 1.03 [1.005, 1.06]). …"

Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway حسب Zhan Y. (4157410)

"…Conclusions: Our study demonstrated a sound conclusion that hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-activated PI3K-Akt signaling pathway in brain, which could serve as a promising therapeutic target for microglia-induced neurodegenerative or emotional disorders in future.…"

Table 1_Transcriptional patterns of brain structural abnormalities in CSVD-related cognitive impairment.docx حسب Haixia Mao (3775582)

"…</p>Results<p>VBM analysis demonstrated extensive decreased GMV in CSVD-related cognitive impairment in the bilateral temporal lobe and thalamus, especially the hippocampus, thalamus, parahippocampus, and fusiform, and the left temporal lobe showed a more severe atrophy than the right temporal lobe. …"

Supplementary file 1_Model-based multi-year P flow analyses and strategies for sustainable food chain management in Changzhou city at China's Taihu Basin.docx حسب Zheng Guo (14989)

"…However, P flows and its balance in many Chinese cities are largely unknown. This study employed the substance flow analysis (SFA) method to construct a P flow model for the food chain in Changzhou, a representative lakeside city in the Taihu Basin. …"

Data Sheet 1_Citywide community-based colorectal cancer screening in urban Shanghai: age and sex variations in risk mitigation from 1973 to 2020.docx حسب Mengyin Wu (8778272)

"…However, elderly mortality decreased significantly (APC: 1.47% to −3.03%, P < 0.001).…"

<b>Chemical components, emission dynamics, and external immune functions of red palm weevil larval volatiles in response to changes in developmental stages and pathogen stress</b> حسب Can-Hui Ding (22140753)

"…However, the volatile compositions, emission patterns, and external immune functions of the red palm weevil (RPW), a major invasive pest, are largely unknown. In this study, we examined RPW larval volatiles, analyzing their chemical composition and emission patterns across developmental stages and under pathogen stress. …"

smFISH probe sequences used in this study. حسب Grace E. Johnson (21376787)

"…To define mechanisms underlying biofilm developmental transitions, we establish a single-molecule fluorescence in situ hybridization (smFISH) approach that enables accurate quantitation of spatiotemporal gene-expression patterns in biofilms at cell-scale resolution. smFISH analyses of <i>V. cholerae</i> biofilm regulatory and structural genes demonstrate that, as biofilms mature, overall matrix gene expression decreases, and simultaneously, a pattern emerges in which matrix gene expression becomes largely confined to peripheral biofilm cells. …"

Strains used in this study. حسب Grace E. Johnson (21376787)

"…To define mechanisms underlying biofilm developmental transitions, we establish a single-molecule fluorescence in situ hybridization (smFISH) approach that enables accurate quantitation of spatiotemporal gene-expression patterns in biofilms at cell-scale resolution. smFISH analyses of <i>V. cholerae</i> biofilm regulatory and structural genes demonstrate that, as biofilms mature, overall matrix gene expression decreases, and simultaneously, a pattern emerges in which matrix gene expression becomes largely confined to peripheral biofilm cells. …"

Water-saving strategies in rice farming entail cascading effects in prey-predator interactions across ecosystem boundaries حسب Néstor Pérez-Méndez (7845404)

"…<i>Synthesis and applications</i><i>:</i> These results show that introducing multiple drainage periods in rice fields (i.e., AWD) indirectly hampers terrestrial spider reproduction through limiting the emergence of potential preys from the aquatic to terrestrial boundaries. MSD resulted in a more conciliatory strategy as it largely reduces methane emissions and does not affect predator-prey interactions, thus it should be prioritized over AWD to minimize environmental trade-offs. …"

Data Sheet 1_Hyaluronan synthase 3 deficiency lowers the incidence of ruptures of abdominal aortic aneurysms by reducing monocyte infiltration.docx حسب Viola Niemann (22572638)

"…Critical pathomechanisms involve immune cell infiltration and degradation of the vascular extracellular matrix (ECM). Hyaluronan (HA), a major constituent of the ECM synthesized by three HA synthase isoenzymes (HAS1-3), plays a role in both processes. …"

Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc حسب Wenping Sun (1465360)

"…However, its underlying mechanisms remain largely elusive.</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…"

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma حسب Maowei Ni (15397932)

"…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …"

Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Image 5_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Image 3_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Image 1_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"