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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
منشور في 2010"…We observed an increased P-gp expression (1.5-fold) in presymptomatic mSOD1 mice compared to wild-type controls. …"
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Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha
منشور في 1998"…We conclude that leptin expression is under partial regulatory control of TNF-α in peritonitis, but the anorexia is not dependent on increased leptin production.…"
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Transcriptome analysis of Escherichia coli K1 after therapy with hesperidin conjugated with silver nanoparticles
منشور في 2021"…Of note, the expression levels of cation efflux genes (cusA and copA) and translocation of ions, across the membrane genes (rsxB) were found to increase 2.6, 3.1, and 3.3- log FC, respectively. …"
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Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting
منشور في 2020"…<h3>Background</h3><p dir="ltr">Despite increasing demand, current protocols for human pluripotent stem cell (hPSC)-derived retinal pigment epithelium (RPE) remain time, labor, and cost intensive. …"
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
منشور في 2021"…Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …"
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Intelligent Rapidly-Exploring Random Tree Star Algorithm
منشور في 2024احصل على النص الكامل
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
منشور في 2023"…BackgroundIn the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …"
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Assessment of network module identification across complex diseases
منشور في 2019"…We launched the ‘Disease Module Identification DREAM Challenge’, an open competition to comprehensively assess module identification methods across diverse protein–protein interaction, signaling, gene co-expression, homology and cancer-gene networks. …"
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HBN Nanoparticle-Assisted Rapid Thermal Cycling for the Detection of Acanthamoeba
منشور في 2020"…As low as 1 X 10¯⁴ wt % was determined as the optimum concentration of hBN nanoparticles, which increased Acanthamoeba DNA yield up to ~16%. Further, it was able to reduce PCR temperature that led to a ~2.0-fold increase in Acanthamoeba DNA yield at an improved PCR specificity at 46.2 °C low annealing temperature. hBN nanoparticles further reduced standard PCR step time by 10 min and cycles by eight; thus, enhancing Acanthamoeba detection rapidly. …"
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Rapid separation of very low concentrations of bacteria from blood
منشور في 2017"…A rapid and accurate diagnosis of the species and antibiotic resistance of bacteria in septic blood is vital to increase survival rates of patients with bloodstream infections, particularly those with carbapenem-resistant enterobacteriaceae (CRE) infections. …"
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Advancing Rapid Arsenic (III) Detection Through Device-Integrated Colorimetry
منشور في 2024"…<p dir="ltr">It is essential to detect precise traces of inorganic arsenic ions when utilized, which may increase the risks of several health issues such as lung, bladder, skin cancer, and diabetes diseases. …"
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Rapid simulation of building physical processes using the coarse-grain method
منشور في 2017"…The paper is concerned with an artificial neural network (ANN) based coarse-grain method (CGM) for rapid simulation of physical processes in buildings, such transient heat-flow, fire propagation, and the circulation/dispersal of fumes or pathogens in a building. …"
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
منشور في 2025"…Kinetic studies showed superior correlation with the pseudo-second-order model (R<sup>2</sup> > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"
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Variational Auto Encoder Approach To Find Deferentially Expressed Genes
منشور في 2022"…A study of differentially expressed genes across different cell types will help in identifying cell-specific responses to treatments or diseases. …"
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
منشور في 2016"…We found significantly higher levels of cells expressing myeloid markers and lacking the expression of major histocompatibility complex class II molecule HLA-DR in blood and tumor of CRC patients. …"
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Differing endometrial expression of calcium modulating transient receptor potential channels
منشور في 2021"…<p dir="ltr">To the editor</p><p dir="ltr">Assisted reproductive techniques (ART) have increased the live birth success rate, but there is still a significant implantation failure rate. …"
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Special issues in breast cancer gene expression profiling in breast cancer
منشور في 2009"…• Gene expression profiling has been increasingly used to determine new cancer markers. …"
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