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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…We observed an increased P-gp expression (1.5-fold) in presymptomatic mSOD1 mice compared to wild-type controls. …”
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Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha
Published 1998“…We conclude that leptin expression is under partial regulatory control of TNF-α in peritonitis, but the anorexia is not dependent on increased leptin production.…”
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy
Published 2021“…Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …”
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
Published 2016“…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …”
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Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…This was associated with increased expression of thioredoxin-interacting protein, curbing entry of glucose into cells; decreased hexokinase-2, curbing entry of glucose into cellular metabolism; decreased 6-phosphofructo-2-kinase, downregulating formation of allosteric enhancer of glycolysis fructose-2,6-bisphosphate; and increased glucose-6-phosphate dehydrogenase, downregulating carbohydrate response element- (ChRE-) mediated transcriptional enhancement of glycolysis by Mondo/Mlx. …”
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Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
Published 2024“…Correction of increased MG by increasing Glo1 expression prevented UPR activation. …”
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Transcriptome analysis of Escherichia coli K1 after therapy with hesperidin conjugated with silver nanoparticles
Published 2021“…Of note, the expression levels of cation efflux genes (cusA and copA) and translocation of ions, across the membrane genes (rsxB) were found to increase 2.6, 3.1, and 3.3- log FC, respectively. …”
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
Published 2021“…<h3>Introduction</h3><p dir="ltr">Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …”
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Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…Interestingly, addition of Exendin-4 (50 nM) during the last 3 days of the differentiation significantly enhanced GSIS associated with increased expression of glucose-sensing apparatus genes (Glut2, G6P2C, GCK) and genes encoding mitochondrial oxidative phosphorylation machinery.…”
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…BackgroundIn the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …”
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Assessment of network module identification across complex diseases
Published 2019“…We launched the ‘Disease Module Identification DREAM Challenge’, an open competition to comprehensively assess module identification methods across diverse protein–protein interaction, signaling, gene co-expression, homology and cancer-gene networks. …”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
Published 2025“…Our research demonstrates high mercury removal efficiency (89–94 %) across all tested concentrations, with rapid kinetics achieving equilibrium within just 2 min of contact time. …”
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Variational Auto Encoder Approach To Find Deferentially Expressed Genes
Published 2022“…A study of differentially expressed genes across different cell types will help in identifying cell-specific responses to treatments or diseases. …”
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Differing endometrial expression of calcium modulating transient receptor potential channels
Published 2021“…<p dir="ltr">To the editor</p><p dir="ltr">Assisted reproductive techniques (ART) have increased the live birth success rate, but there is still a significant implantation failure rate. …”
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Special issues in breast cancer gene expression profiling in breast cancer
Published 2009“…• Gene expression profiling has been increasingly used to determine new cancer markers. …”
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