Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin–angiotensin-aldosterone system (RAAS) dysregulation حسب Robin Augustine (3976964)

Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis حسب Susie S. Y. Huang (2824502)

"…Septic stimulation induced a significant increase in ERLIN1 expression; however, ERLIN1 was differentially expressed among the immune blood cell subsets. …"

Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study حسب Alexandra E. Butler (6189536)

Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system حسب Frank Schmidt (207186)

Micro-Expression Recognition using Convolutional Variational Attention Transformer (ConVAT) with Multihead Attention Mechanism حسب Hafiz Khizer bin Talib (20571467)

"…Despite significant advancements in deep learning models, challenges persist in accurately handling the nuanced and fleeting nature of micro-expressions, particularly when applied across diverse datasets with varied expressions. …"

Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta... حسب Mohammed M. Al-Humaiqani (18325554)

"…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. Achieving resilience objectives in the built environment is challenging and requires the collaboration of all relevant sectors and professionals. …"

Methionine mediates resilience to chronic social defeat by modulating NMDA receptor expression in the cortex. (c2018) حسب Bilen, Maria

"…This increase was accompanied by a reduction in the protein levels of the histone methyltransferase known to modulate NMDA receptor expression, SetDB1 in defeated animals, while methionine injections returned SetDB1 levels to baseline. …"
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Comprehensive Transcriptomic Profiling of Murine Osteoclast Differentiation Reveals Novel Differentially Expressed Genes and LncRNAs حسب Salman M. Toor (8854751)

"…Notably, we report Nol4 as a novel gene related to osteoclast activity since Nol4 knockout mice Nol4em1(International Mouse Phenotyping Consortium)J exhibit increased bone mineral density. Moreover, the differentially expressed LncRNAs included antisense and long intergenic non-coding RNAs, among others. …"

Recombinant Adeno-Associated Virus-Mediated In Utero Gene Transfer Gives Therapeutic Transgene Expression in the Sheep حسب Abi Nader, Khalil

"…This is the first study to show therapeutic long-term hFIX transgene expression after in utero gene transfer in a large animal model.…"
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? حسب Abu Saleh Md Moin (6189512)

"…<h3>Introduction</h3><p dir="ltr">Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …"

Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats حسب Barakat, Ghinwa

"…Therefore, exendin-4 and selenium may exert their antidiabetic effects by increasing GLP-1R, IRS-1, and preproinsulin expression in the pancreas and by increasing the number of pancreatic islets.…"
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Comprehensive analysis of circulating miRNA expression profiles in insulin resistance and type 2 diabetes in Qatari population حسب Khaoula Errafii (10914446)

Comparative transcriptomics of primary cells in vertebrates حسب Tanvir Alam (638619)

"…While we find that expression profiles of orthologous genes in different species are highly correlated across cell types, in each cell type many genes were differentially expressed between species. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…<p dir="ltr">Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. …"

Prenatal psychological distress and 11β-HSD2 gene expression in human placentas: Systematic review and meta-analysis حسب Angham Ibrahim Tartour (19756953)

"…</p><h3>Results</h3><p dir="ltr">Of 3159 retrieved records, sixteen longitudinal studies involving 1869 participants across seven countries were included. Overall, exposure to PPD disorders showed weak negative associations with the placental <i>11-β HSD2</i> gene expression as follows: prenatal depression (β −0.01, 95% CI 0.05–0.02, I2=0%), anxiety symptoms (β −0.02, 95% CI 0.06–0.01, I2=0%), and perceived stress (β −0.01 95% CI 0.06–0.04, I2=62.8%). …"

First Whole Transcriptome RNAseq on CHD8 Haploinsufficient Patient and Meta-Analyses Across Cellular Models Uncovers Likely Key Pathophysiological Target Genes حسب Heba Yasin (14152542)

"…We found that concordance among differential gene expression profiles was poor across all datasets. Nevertheless, remarkably, we show that the patient blood differential gene expression profile most resembled that of the neuronal cell model, a finding that encourages further transcriptome profiling using patient blood samples. …"

Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats حسب Rizk, Sandra

"…Therefore, exendin-4 and selenium may exert their antidiabetic effects by increasing GLP-1R, IRS-1, and preproinsulin expression in the pancreas and by increasing the number of pancreatic islets.…"
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…Tumorsphere formation in breast cancer cells enhanced epithelial to mesenchymal transition (EMT), which is evident by increased expression of mesenchymal markers. In this study, we analyzed CpG methylation of PD-L1 promoter in MCF-7 and BT-549 breast cancer cells and tumorspheres derived from them. …"

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1 حسب Bushra Memon (4792767)

"…These dissociated cells were subjected to an augmented duration of retinoid and fibroblast growth factor (FGF)10 signaling to induce higher PDX1 and NKX6.1 expression.</p><h3>Results</h3><p dir="ltr">Our optimized protocol dramatically increased the expression of NKX6.1, leading to an increase in the proportion of PDX1⁺/NKX6.1⁺ progenitors (~90%) in monolayer, higher than the previously published protocols, as well as upregulated key TFs controlling pancreatic development. …"