Leishmania major by Daher, Costantine F.

“…Infected rats received daily injections of rIL-13 for eight consecutive days which resulted in increased pain perception for the first week post-infection assessed by thermal pain tests. …”
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Roles of RhoA, RhoC and RhoG in Secretion of Vascular Endothelial Growth Factor (VEGF) by Astrocytoma Cells and Angiogenesis in Vascular Endothelial Cells. (c2015) by Fakih, Amira K.

“…As the tumor size increases, cancer cells stimulate neighboring vascular endothelial cells to proliferate and form new blood vessels in order to irrigate the tumor. …”
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The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption by Sachin Wani (11704868)

“…We found that the PDB-risk allele of rs5742915 was associated with lower PML expression and that PML expression in blood cells from individuals with PDB was lower than in controls. …”

Gasoline fume inhalation induces apoptosis, inflammation, and favors Th2 polarization in C57BL/6 mice by Nour-Eldine, Wared

“…Interestingly, IL-10 expression was also increased by ~ 10-fold in the lungs of GE mice suggesting an attempt to counterbalance the established inflammation. …”
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Schizophrenia-related dysbindin-1 gene is required for innate immune response and homeostasis in the developing subventricular zone by Abeer R. Al-Shammari (11405339)

“…PolyI:C also increased SVZ Dtnbp1 mRNA expression, suggesting dysbindin-1 regulates immune responses. …”

The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase by Kthiri, Fatoum

“…YbbN specifically interacts with DnaK and GroEL, as shown by reverse purification. It increases 4-fold the rate of protein renaturation in vitro by the DnaK chaperone machine, suggesting that it cooperates with DnaK for the optimal expression of several cytoplasmic proteins.…”
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The relationship of soluble neuropilin-1 to severe COVID-19 risk factors in polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…Therefore, tissues enriched for NRP1 have increased infectivity risk [1] and subjects expressing increased NRP1 may have increased risk.…”

Enhancing Thermal Comfort for the Revitalization of Pedestrian-Friendly Shopping Arcades in Dubai, UAE by RAJEEV, ANN MARIA

“…The need for globalization in the current world has made it impossible for a slow and steady growth in the world’s population. This rapid growth directly influences the economic, environmental and social aspects within a society. …”
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Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy by Chaoul, Victoria

“…Expression of PKA subunits (RI, RIIα and Cα) remained unchanged regardless of the disease stage, whereas CaMKII increased at Week 12 in DCM. …”
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Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Furthermore, the combination therapy upregulates protein expression levels of pro-apoptotic proteins Bax, p53 and cytochrome c, downregulates the expression of antiapoptotic Bcl-2 protein and increases the cleavage of procaspases 8 and 9; this suggests that the combination activates apoptosis via both the intrinsic and extrinsic pathways. …”
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Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF by Jabr, Vanessa

“…Indeed, we showed that short-term voluntary wheel running increases the protein expression levels of the autophagy marker, protein light chain 3 (LC3B), in the hippocampus of 10-week-old mice. …”
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Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation by Sleiman, Sama F.

“…Forced expression of TG1 or TG2 proteins is sufficient to induce neuronal death in Rattus norvegicus cortical neurons in vitro. …”
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Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma by AbouAntoun, Thamara Jihad

“…Expression of the platelet-derived growth factor receptor (PDGFR) correlates with metastatic medulloblastoma and PDGF treatment of medulloblastoma cells activates the pro-survival and pro-migratory pathways downstream of the receptor, for instance, increases extra-cellular regulated kinase (Erk1/2), Protein kinase B (Akt) and phosphatidylinositide 3-kinase (PI3K) activity and decreases phosphatase and tensin homolog (PTEN) expression and activity. …”
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Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose by Roberta Giordo (299595)

“…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …”

Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics by Abbas Khan (5141000)

“…Survival analysis results revealed a strong association between <i>RAF1</i> and <i>RAP1A</i> expression levels and diminished survival rates in cancer patients across different cancer types. …”

Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine by Hamda A. Al-Naemi (14151675)

“…This protein expression was similar to the control group after the withdrawal of Cd treatment. …”

A curated collection of transcriptome datasets to investigate the molecular mechanisms of immunoglobulin E-mediated atopic diseases by Susie S Y Huang (18805921)

“…Thirty-three datasets from the Gene Expression Omnibus, encompassing 1860 transcriptome profiles, were made available on the Gene Expression Browser (GXB), an online and open-source web application that allows for the query, visualization and annotation of metadata. …”

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…The effects of increased endogenous ceramides could be offset by sphingosine 1-phosphate (S1P), a prosurvival by-product of ceramide metabolism. …”
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PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer by Reem Saleh (3513056)

“…<div><p>Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. …”

Indirect measurement of aneurysm wall thickness using digital stethoscope by Jou, Liang-Der

“…Aneurysms at 6 mm produced very low frequency sound. Wall thickness decreases with aneurysm size, and the decrease is more pronounced at 8 mm. …”
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