Data Sheet 1_Integrated transcriptomic analysis identifies lactylation-linked gemcitabine resistance and therapeutic targets in intrahepatic cholangiocarcinoma.docx حسب Wenwei Xie (1987225)

"…</p>Methods<p>A comprehensive bioinformatics analysis was conducted using publicly available transcriptomic data from gemcitabine-resistant iCCA cell lines and patient samples. …"

<i>CHGA</i> mRNA expression decreases with <i>CYB561</i> knockdown. حسب Romie Angelo G. Azur (18547651)

Relevant gene information for important mutation sites for 33 BBS. حسب Zengwen Huang (11523364)

Tumors from vehicle-treated mice were collected at the end of study, homogenized, and assessed for expression of FGFR1, vimentin, and β-actin. حسب Angela Abdollahi (15166230)

Low ATF3 expression is associated with decreased survival and EZH2 and ATF3 signatures inversely correlate in human prostate cancers. حسب Amy E. Schade (15368259)

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NeuroD1/GPX4 axis promotes HCC cell ferroptosis resistance and tumorigenic potential. حسب Ping Huang (30439)

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Catalase promotes oxidative stress resistance but is not required for glucose-enhanced oxidative stress resistance. حسب Daniel E. Larcombe (16521053)

<i>CYB561</i> knockdown decreased the survival, proliferation, and migration rates of PC-3 cells. حسب Romie Angelo G. Azur (18547651)

Loss-of-function of Mp<i>RTN4IP1L</i> confers resistance to thaxtomin A. حسب Chloe Casey (14341756)

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NeuroD1 directly binds to the <i>GPX4</i> promoter and regulates its transcriptional activity in MHCC-97H cells. حسب Ping Huang (30439)

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NeuroD1 inhibits HCC cell ferroptosis. حسب Ping Huang (30439)

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NeuroD1 positively regulates GPX4. حسب Ping Huang (30439)

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Schematic diagram showing the role of NeuroD1/GPX4 axis on HCC cell ferroptosis resistance and tumorigenesis. حسب Ping Huang (30439)

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NeuroD1 enhances HCC cell viability and colony formation potential. حسب Ping Huang (30439)

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NeuroD1 directly binds to the <i>GPX4</i> promoter and regulates its transcriptional activity. حسب Ping Huang (30439)

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All numerical and statistical data for quantitation figures. حسب Ping Huang (30439)

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<i>NeuroD1</i> overexpression abolished the effect of knocking down <i>NeuroD1</i> on ferroptosis. حسب Ping Huang (30439)

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NeuroD1/GPX4 axis regulates HCC cell viability and colony formation potential. حسب Ping Huang (30439)

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Efficacies of shRNA expression vectors targeting <i>NeuroD1</i> and <i>NeuroD1</i> overexpression vector. حسب Ping Huang (30439)

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NeuroD1 suppresses ferroptosis by upregulating GPX4. حسب Ping Huang (30439)

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