A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Further, mutational analysis revealed a requirement for both cleavage sites to be intact for increased cleavage rate. Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion by Bushra Memon (4792767)

Biomarkers show promise for treatment of heart valve disease by Nature Research (16552612)

“…The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …”

Do social responsibility disclosures show improvements on stock price? by Jizi, Mohammad

“…The research examines a sample of national commercial banks, as the banking sector was experiencing increasing pressure that scratched stakeholders and investors trust during the latest financial crisis. …”
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Recombinant prostate-specific antigen proaerolysin shows selective protease sensitivity and cell cytotoxicity by Abi-Habib, Ralph

“…Recombinant modified proaerolysin had no furin sensitivity and markedly increased prostate-specific antigen sensitivity relative to wild-type proaerolysin. …”
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Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy by Hanna, Rita

“…Upregulation of β1-AR receptor transcripts was noted in diabetic hearts at 4 weeks along with an increase in cAMP levels and an upregulation in the ejection fraction and fraction shortening. …”
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Kinetics and mechanisms of ceramide increases in experimental status epilepticus by Abi-Habib, Ralph Joseph

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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Performance and microbial community variations of anaerobic digesters under increasing tetracycline concentrations by Xiong, Yanghui

“…An increase in the abundance of tetracycline resistance genes associated with ribosomal protection proteins was observed after 30 days of exposure to high concentrations of tetracycline, while other targeted resistance genes showed no significant changes. …”
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Effect of increasing the number of anchors on the flexural performance of FRP-strengthened RC beams by Hawileh, Rami A.

“…The first beam was strengthened and unanchored, and the other two beams were strengthened and anchored with one or two 14-mm diameter FRP anchors on each side, respectively. Results showed that increasing the number of anchors significantly improved the flexural behavior of the strengthened beam in terms of the beam's response at failure and the strain utilized in the FRP laminates. …”
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Potential of horizontal louvers in increased energy savings in a commercial building in Dubai by BORDAWEKAR, SANIYA

“…Dimmer sensor configuration shows about 10-15 % increase in energy savings than the configuration with sensor off. …”
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Increase of satellite tobacco ringspot virus RNA initiated by inoculating circular RNA by Buzayan, Jamal M.

“…These results are consistent with models for the replication of the satellite RNA in which a circular form of the satellite RNA is a template for rolling circle transcription or is otherwise a replication intermediate or is readily converted to an intermediate. We also show that a circular form of a nonaccumulating satellite RNA mutant induced an increase in a satellite RNA that is endogenous to some tobacco ringspot virus virion preparations, as demonstrated previously for the linear form.…”
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Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats by Zeeni, Nadine

“…The intake of T. porrifolius aqueous extract therefore improved lipemia and increased satiety in rats with no visible adverse effects.…”
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …”

The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis by Ahmad R. Al-Qudimat (17337808)

“…Meta-regression analysis results also showed a statistically significant association between hypertension and COVID-19 mortality.…”

Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline by Ramya Potabattula (4401160)

“…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. …”

Triple helix components supporting STEM education to increase future STEM careers in the United Arab Emirates by Husain, Fatima Yousif

“…Increasing communication between government schools, universities, and industry can benefit STEM education programs and STEM careers. …”
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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease by Nour K. Majbour (8809316)

“…ROC analysis showed a sensitivity of 85% and a specificity of 84% (AUC = 0.88) in distinguishing AD from controls. …”

Effective Approach for Increasing the Heteroatom Doping Levels of Porous Carbons for Superior CO2 Capture and Separation Performance by Abdelmoaty, Yomna H

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