The effect of IFN-β and Vit D on the IL-1β and IL-10 protein production. by Farzad Nasri (8941850)

“…IFN-β and Vit D alone or together decreased IL-1β and IL-10 protein level, significantly in comparison with the control <b>(A, B)</b>. …”

High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection by Yiwei Zhang (1448599)

“…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …”

Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf by Stephanie DeStefano (15457187)

“…Analysis of epithelial cell markers revealed decreased gene expression of the tight junction proteins Cld-18 and Tjp-1, and decreased expression of the epithelial transmembrane protein E-cadherin in the lungs of naïve NLRP3^-/- mice compared to WT mice. …”

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

“…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”

Data Sheet 1_Inhibition of biofilm formation and preformed biofilm in Acinetobacter baumannii by resveratrol, chlorhexidine and benzalkonium: modulation of efflux pump activity.zip by Antonella Migliaccio (12052292)

“…The combination of RV with CHX and BZK additively decreased minimal biofilm eradicating concentrations in A. baumannii strains.…”

<b>Glucose</b><b>-6-Phosphatase Catalytic Subunit 3 Enhances Host Resistance to Porcine Epidemic Diarrhea Virus Through Regulating </b><b>Glycolysis/Gluconeogenesis</b> by Huihui Li (22299664)

“…<p dir="ltr"><a href="" target="_blank">Porcine epidemic diarrhea virus (PEDV) causes a highly contagious disease in pigs, and the intricacies of its host-pathogen interactions require further elucidation</a>. …”

S1 Data - by Yumeng Zhang (3115050)

“…The results of this study suggest that the level of well-being as a whole, as well as in the eastern, central and western regions increased significantly over the period, with an “east-to-west decreasing” distribution in China. …”

Index system for well-being level. by Yumeng Zhang (3115050)

“…The results of this study suggest that the level of well-being as a whole, as well as in the eastern, central and western regions increased significantly over the period, with an “east-to-west decreasing” distribution in China. …”

Supplementary Material for: Gut microbiome composition and one-year survival outcomes among patients with reduced ejection fraction heart failure by figshare admin karger (2628495)

“…Results: HFrEF patients showed a significantly lower abundance of all bacterial taxa, except for A. muciniphila. …”

Candidate genes by Genome-wide CRISPR Screen. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat... by P. Kavya (21356483)

“…<p>Curcuma angustifolia Roxb. is a therapeutic herb and a member of the Zingiberaceae family. …”

Supplementary file 1_Embryo-derived trypsin-induced calcium entry is inhibited by endometrial infertility factor, LEFTY2.docx by Zhiqi Yang (2692909)

“…In the presence of nifedipine, LEFTY2 did not further modify trypsin induced increase of [Ca²⁺]_i. LEFTY2 significantly decreased levels of L-type Ca²⁺ channel.…”

Supplementary Material for: The role of neutrophils in venous thrombosis in primary membranous nephropathy by figshare admin karger (2628495)

“…In animal experiments, the plasma cfDNA levels elevated significantly after IVC stenosis in PHN rats, and GSK484 decreased the plasma cfDNA levels in PHN rats with IVC stenosis. 4 hours after IVC stenosis surgery, thrombi formed in PHN rats were both longer and heavier compared to those observed in control rats, and GSK484 administration significantly inhibits the thrombus formation in PHN rats. …”

Data Sheet 1_Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells.pdf by Nadezhda Logunova (831700)

“…<p>Previously we have shown that H2-congenic recombinant mice of the B6.I-9.3 (H2-Ab1^j) strain are significantly more susceptible to tuberculosis (TB) infection compared to their C57BL/6 (B6, H2-A^b) ancestors. …”

Design, synthesis and biological evaluation of non-glucosidal based 1,3,4-thiadiazoles as SGLT-2 inhibitors by Shivani Sharma (255210)

“…SSS 6 and SSS 2 significantly decreased blood glucose levels (137 ± 4.89 mg/dL and 183 ± 15.07 mg/dL) relative to dapagliflozin (158 ± 15.9 mg/dL).…”

Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pat... by Yu Lai (764498)

“…This study investigates the therapeutic effects and underlying mechanisms of LD on CVA.</p> <p>A guinea pig CVA model was treated with either LD or budesonide (BUD). …”