High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection by Yiwei Zhang (1448599)

“…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …”

Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf by Stephanie DeStefano (15457187)

“…Analysis of epithelial cell markers revealed decreased gene expression of the tight junction proteins Cld-18 and Tjp-1, and decreased expression of the epithelial transmembrane protein E-cadherin in the lungs of naïve NLRP3^-/- mice compared to WT mice. …”

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

“…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”

S1 Data - by Yumeng Zhang (3115050)

“…The results of this study suggest that the level of well-being as a whole, as well as in the eastern, central and western regions increased significantly over the period, with an “east-to-west decreasing” distribution in China. …”

Index system for well-being level. by Yumeng Zhang (3115050)

“…The results of this study suggest that the level of well-being as a whole, as well as in the eastern, central and western regions increased significantly over the period, with an “east-to-west decreasing” distribution in China. …”

Candidate genes by Genome-wide CRISPR Screen. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat... by P. Kavya (21356483)

“…<p>Curcuma angustifolia Roxb. is a therapeutic herb and a member of the Zingiberaceae family. …”

Supplementary file 1_Embryo-derived trypsin-induced calcium entry is inhibited by endometrial infertility factor, LEFTY2.docx by Zhiqi Yang (2692909)

“…In the presence of nifedipine, LEFTY2 did not further modify trypsin induced increase of [Ca²⁺]_i. LEFTY2 significantly decreased levels of L-type Ca²⁺ channel.…”

Design, synthesis and biological evaluation of non-glucosidal based 1,3,4-thiadiazoles as SGLT-2 inhibitors by Shivani Sharma (255210)

“…SSS 6 and SSS 2 significantly decreased blood glucose levels (137 ± 4.89 mg/dL and 183 ± 15.07 mg/dL) relative to dapagliflozin (158 ± 15.9 mg/dL).…”

Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pat... by Yu Lai (764498)

“…This study investigates the therapeutic effects and underlying mechanisms of LD on CVA.</p> <p>A guinea pig CVA model was treated with either LD or budesonide (BUD). …”

Image 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.jpg by Jiajun Chen (1279269)

“…</p>Conclusion<p>The enrichment of Prevotella melaninogenica species in LRT and a decreased level of peripheral blood lymphocytes are associated with CIP/RP.…”

Data Sheet 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.zip by Jiajun Chen (1279269)

“…</p>Conclusion<p>The enrichment of Prevotella melaninogenica species in LRT and a decreased level of peripheral blood lymphocytes are associated with CIP/RP.…”

Table 1_Changes in rat plasma proteomes during the first week after birth.docx by Lilong Wei (426321)

“…The plasma of first-week rats, compared to that in newborn rats using label-free quantification, showed that the levels of 42 proteins significantly increased while those of 17 proteins decreased. …”

Table 2_Changes in rat plasma proteomes during the first week after birth.xlsx by Lilong Wei (426321)

“…The plasma of first-week rats, compared to that in newborn rats using label-free quantification, showed that the levels of 42 proteins significantly increased while those of 17 proteins decreased. …”

Conditional Knockout of Serine Racemase in Microglia Alleviates Alzheimer -like Pathology and Behavior by Reducing Neuroinflammation through Enhancing Histone Lactylation by shengzhou Wu (22341388)

“…Further, addition of C646, a p300 inhibitor or oxamate, an inhibitor of lactate dehydrogenase A, significantly reversed arginase1 or interleukin-10 mRNA levels in srr-/- microglia. …”

DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf by Gabriela Gajek (4060549)

“…COLEC11 heterozygosity for the activity-decreasing polymorphism (rs7567833, +39618 A>G, His219Arg) was more common in preterm premature rupture of membranes (pPROM) cases, compared with corresponding reference groups. …”

DataSheet1_Type I-conventional dendritic cells support the progression of multiple myeloma in the bone marrow.docx by Sayaka Suzuki (248729)

“…Consequently, the frequencies of exhausted CD8 T cells and regulatory T cells significantly decreased in the bone marrow of cDC1-depleted mice.…”

Data Sheet 1_Dynamic brain network reconfiguration following rTMS in males with cocaine use disorder.pdf by Chengjie Le (22099766)

“…Although FPCN-state self-transition decreased significantly following stimulation, it was not directly linked to craving improvement, indicating a potentially supportive but nonspecific role in perceptual recalibration. …”

Table1_Rethinking the prognosis model of differentiated thyroid carcinoma.docx by Liang He (305820)

“…More patients were classified as stage I, and the number of stage IV patients decreased significantly. The new system had a higher proportion of variance explained (PVE) (5.04%) and lower Akaike information criterion (AIC) (18,331.906) than the 8th TNM staging system (a PVE of 4.11% and AIC of 18,692.282). …”

Ameliorative impact of Juniperus Macrocarpa extract on methotrexate-induced hepatic damage in rats by Shahad Hassan Hadi (20141025)

“…Rats in groups 3 and 4 were given daily dosages of 100 mg and 200 mg of Juniperus macrocarpa aqueous extract, respectively, for two weeks before receiving a single intraperitoneal MTX injection. Juniperus macrocarpa extracts at both low and high doses substantially alleviated the MTX-provoked biochemical alterations, as evidenced by decreased levels of inflammatory parameters including TNF-α and IL-6 and hepatic enzymes including ALT, AST, and ALP. …”