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20681
Bacterial Dynamics in the Northern Indian Ocean Region: Understanding from the Pre-genomics to Present-Day OMICS Era
Published 2024“…Molecular techniques and 16S rRNA gene sequencing introduced after the late 1990s significantly enhanced the understanding of bacterial diversity. …”
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20682
Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx
Published 2025“…</p>Results and discussion<p>We established three dosage groups (2.5 × 10<sup>8</sup>, 5 × 10<sup>8</sup>, and 1.5 × 10<sup>9</sup> CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …”
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20683
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
Published 2024“…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …”
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20684
Table 6_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20685
Table 4_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20686
Supplementary file 1_Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites.zip
Published 2025“…In addition, the levels of steroids, phenolic compounds, and flavonoids were also significantly increased in NZJB and XZJB. Transcriptome analysis revealed significant differences in the expression of genes involved in the biosynthesis of antcins and antrodin C across the different cultivation methods. …”
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20687
Table 7_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20688
Table 1_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20689
Supplementary file 1_Fecal microbiota transplantation augments 5-fluorouracil efficacy in pancreatic cancer via gut microbiota modulation.zip
Published 2025“…The FMT + 5FU group showed a significant reduction in cytokine levels, including TNF-α (p = 0.0001) and IL-6 (p = 0.012) and increased IL-10 level (p < 0.001), compared to the Model group. …”
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20690
Data Sheet 1_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.pdf
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20691
Table 3_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20692
Table 2_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20693
Table 5_Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.xlsx
Published 2024“…First, both the epithelial and submucosal compartments showed diverse but significant upregulation of humoral immune responses, as indicated by the expression of several antibody-related genes. …”
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20694
Table_1_Olfactory dysfunction as an early pathogenic indicator in C. elegans models of Alzheimer's and polyglutamine diseases.xlsx
Published 2024“…Notably, AWB neurons in both models showed significantly shortened cilia and increased instances of enlarged cilia as early as day 1 of adulthood. …”
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20695
Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury
Published 2025“…Furthermore, the levels of p-AKT and p-S6 decreased after ACOT4 and ACOT6 knockdown and increased following ACOT4 and ACOT6 overexpression, suggesting that both ACOT4 and ACOT6 activated Akt/mTOR signaling pathway in HK-2 cells. …”
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20696
Data Sheet 1_Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to d...
Published 2025“…</p>Results<p>The 100g group had significantly higher 1h and 2h blood glucose levels than the 75g group (p < 0.01);Under the IADPSG criteria, there were no significant differences in GDM detection rates, positive case characteristics, or maternal-neonatal outcomes between the two groups (p > 0.05);Blood glucose levels at different time points were correlated within each group, no glucose rise difference occurred between groups at 0-1h [Difference in slope (95% CI): 0.127 (-0.092 to 0.346), p>0.05]. …”
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20697
Conditional Knockout of Serine Racemase in Microglia Alleviates Alzheimer -like Pathology and Behavior by Reducing Neuroinflammation through Enhancing Histone Lactylation
Published 2025“…Further, addition of C646, a p300 inhibitor or oxamate, an inhibitor of lactate dehydrogenase A, significantly reversed arginase1 or interleukin-10 mRNA levels in srr-/- microglia. …”
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20698
Image4_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff
Published 2024“…It is anticipated that ocean warming may cause decreased biodiversity in marine tropical areas, as increasing temperatures may lead to the development of a new thermal niche in these regions. …”
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20699
DataSheet1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.pdf
Published 2024“…It is anticipated that ocean warming may cause decreased biodiversity in marine tropical areas, as increasing temperatures may lead to the development of a new thermal niche in these regions. …”
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20700
Image2_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff
Published 2024“…It is anticipated that ocean warming may cause decreased biodiversity in marine tropical areas, as increasing temperatures may lead to the development of a new thermal niche in these regions. …”