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significance » significantly (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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21281
Table 1_Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture.docx
Published 2025“…</p>Results<p>The results showed that elastase exposure led to significant lung damage, including enlarged airspaces, increased collagen deposition and upregulated expression of collagen I/III and MMP9. …”
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21282
Table 4_Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation.pdf
Published 2025“…All ingredients except carnosine significantly reduced TEER (p < 0.05) often with downregulation of barrier genes. …”
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21283
Supplementary file 1_Pre-release environmental acclimation enhances wild adaptability of endangered Kaluga sturgeon (Huso dauricus): insights from digestive, immune, and gut-microb...
Published 2025“…In addition, compared with the control group, the pro-inflammatory cytokine Interleukin-6 (IL-6) was significantly up-regulated, whereas the anti-inflammatory genes Interleukin-10 (IL-10) and Transforming growth factor-beta (TGF-β) were significantly down-regulated in HC4 group (P < 0.05). …”
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21284
Table 2_Reduced ovarian reserve among female offspring of consanguineous marriages in the Middle East—a mini review.docx
Published 2025“…Despite evidence that consanguineous marriages increase genetic risks through increased levels of homozygosity, which might lead to gene dysfunction, their impact on female fertility remains unclear. …”
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21285
Table 3_Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation.xlsx
Published 2025“…All ingredients except carnosine significantly reduced TEER (p < 0.05) often with downregulation of barrier genes. …”
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21286
Presentation 1_Spatial heterogeneity reveals an evolutionary signature predicting therapeutic response and clinical outcomes in hepatocellular carcinoma.pdf
Published 2025“…The HCC evolutionary signature (HCCEvoSig) was developed and assessed across six cross-platform HCC cohorts.</p>Results<p>Genes exhibiting high intra- and inter-tumor expression variation were significantly enriched in a gene set associated with HCC prognosis, from which we developed and validated a reproducible and robust transcriptomic signature, HCCEvoSig. …”
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21287
Table 1_Light-induced epigenetic modifications in the hypothalamus during avian embryonic development enhance phenotypic plasticity.xlsx
Published 2025“…Epigenetically, GMI exposure increased phosphorylated CREB1 (pCREB1) binding levels and chromatin accessibility at specific gene promoters, underscoring the role of light-induced developmental programming. …”
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21288
Data Sheet 1_Exploring the predictive “psycho-biomarkers” for checkpoint immunotherapy in cancer.zip
Published 2025“…To date, no studies have explored the potential of depression-related genes in predicting response to ICIs therapy.</p>Methods<p>Public datasets of ICIs-treated patients were obtained from the TCGA and GEO databases, followed by comprehensive analyses, including bulk mRNA sequencing (mRNA-seq), co-expression network construction, and Gene Ontology enrichment. …”
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21289
Data Sheet 1_An animal-type Na+/K+-ATPase, PhNKA2, is involved in the salt tolerance of the intertidal macroalga Pyropia haitanensis.zip
Published 2025“…The heterologous expression of PhNKA2 in Chlamydomonas reinhardtii clearly increased salt tolerance. Na<sup>+</sup> efflux and K<sup>+</sup> influx were significantly greater in the transgenic C. reinhardtii than in the wild-type control. …”
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21290
Table 1_Reduced ovarian reserve among female offspring of consanguineous marriages in the Middle East—a mini review.docx
Published 2025“…Despite evidence that consanguineous marriages increase genetic risks through increased levels of homozygosity, which might lead to gene dysfunction, their impact on female fertility remains unclear. …”
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21291
Data Sheet 1_Microbial community structure and resistome dynamics on elevator buttons in response to surface disinfection practices.docx
Published 2025“…</p>Conclusion<p>The structure of bacterial communities on elevator button surfaces varies across different environments, likely influenced by the frequency of disinfectant use. Increased resistance gene abundance in quarantine hotels suggests that disinfection practices may contribute to the selection and spread of resistant bacteria. …”
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21292
Table 1_Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation.xlsx
Published 2025“…All ingredients except carnosine significantly reduced TEER (p < 0.05) often with downregulation of barrier genes. …”
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21293
Table 2_Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation.docx
Published 2025“…All ingredients except carnosine significantly reduced TEER (p < 0.05) often with downregulation of barrier genes. …”
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21294
Data Sheet 1_Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation.pdf
Published 2025“…All ingredients except carnosine significantly reduced TEER (p < 0.05) often with downregulation of barrier genes. …”
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21295
Table 1_Predicting immune-related adverse events in patients with melanoma: the role of interleukin-7 rs16906115 polymorphism and lymphocyte dynamics.docx
Published 2025“…Subgroup analyses revealed a significant increase in risk across endocrine, non-cutaneous, multiple, low-grade, and early onset (<3 months) irAEs. …”
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21296
Image 1_A prognostic framework integrating endoplasmic reticulum stress dynamics reveals clinical stratification and differential prognostic attributes in osteosarcoma patients.tif
Published 2025“…We developed a robust ER stress model comprising ten ER stress-associated genes specifically tailored for osteosarcoma patients. …”
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21297
Data Sheet 1_Identifying fecal microbiota signatures of colorectal cancer in a Vietnamese cohort.pdf
Published 2024“…The total community DNA of microorganisms was extracted from the fecal samples and analyzed for microbiota composition using Illumina MiSeq amplicon sequencing targeting the V3–V4 region of the 16S rRNA gene.</p>Results<p>We identified a significant difference in the overall fecal microbiota composition between CRC patients and healthy controls, and we detected several CRC-associated microbial signatures in fecal samples of Vietnamese patients with CRC, which overlapped with signatures from other countries and meta-analyses. …”
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21298
Supplementary Material for: Angiopausin® and Angiopoietin: Unveiling New Mechanisms in Rosacea Treatment through Kinetic Erythema Analysis with the AAREA® Algorithm
Published 2025“…A high level of agreement (R2= 0.9566) was observed between the clinical IEA scores and the algorithm-assisted approach. …”
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21299
Table 1_Probabilistic human health risk assessment of commercially supplied jar water in Gopalganj municipal area, Bangladesh.docx
Published 2024“…Temperature, potential of hydrogen (pH), total dissolved solids (TDS), electrical conductivity (EC), and salinity showed significant variation among the samples, and the level was within the national and international standard limits. …”
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21300
Image1_Association between vitamin C intake and thyroid function among U.S. adults: a population-based study.tiff
Published 2024“…</p>Conclusion<p>The findings of our study have illustrated a notable correlation between vitamin C intake and thyroid function. A high level of vitamin C intake is associated with a decreased in TT4 levels among American adults, and the association was more pronounced among subjects with lower alcohol consumption. …”