Data Sheet 8_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx حسب Shengyou Song (22391068)

"…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…"

Image 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg حسب Jiashuo Li (7865036)

"…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…"

Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx حسب Thibaud Dauphin (21196820)

"…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …"

Table 1_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx حسب Giacomo Brisca (10963929)

"…The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …"

Data Sheet 1_PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution.docx حسب Lin Zhang (8926)

"…Notably, we observed significant changes in immune cell populations, including reductions in macrophages (510 to 58 cells), NK cells (445 to 91 cells), and granulocytes (1597 to 1 cells). …"

Inner-IoU. حسب Chunhua Yang (346871)

"…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …"

Image 5_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg حسب Chaofeng Niu (17746406)

"…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …"

Data Sheet 1_The impact of landscape patterns on surface runoff in the central urban area of Chengdu.docx حسب Ying Kang (2503126)

"…When the proportions of farmland and forestland were low, their effectiveness in reducing runoff decreased with increasing rainfall intensity. Similarly, the impact of impervious surfaces also diminished with increasing rainfall intensity. ④ The SSRLI demonstrated good applicability in predicting changes in surface runoff, showing a significant positive correlation with runoff depth. …"

Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf حسب Maxim Sorokin (4379848)

"…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …"

Workflow of the study. حسب Hongliang Chen (538815)

"…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …"

Table 1_Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins.docx حسب Min Luo (258201)

"…Western blot analysis validated these findings in plasma samples, showing significantly increased expression of MMP12 and ASM, and decreased expression of NPNT and SNX1 in COPD patients compared to healthy controls, while KLC1 showed no significant difference. …"

Data Sheet 1_From psychological wellbeing to distress: the role of psychological counseling interventions in university students.pdf حسب Francesco Craig (8214780)

"…Post-intervention, psychological distress decreased significantly (p < 0.001), with 56.7% of students falling over the clinical distress cut-off at T1 compared to 84.4% at T0. …"

What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting? حسب Rafael Freitas (16738416)

"…</p><p dir="ltr"><b>Conclusions/Significance:</b> The density of In2Care stations varied across neighborhoods, ranging from 220 to 555 stations per km². …"

Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease حسب Halil Onder (10368032)

"…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …"

Data_Sheet_1_Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study.docx حسب Chong Li (120471)

"…</p>Results<p>The BMI and 28-day mortality exhibited an L-shaped relationship (p for nonlinearity <0.001) with significant gender-specific differences. Subgroup analysis revealed different association patterns between the male and female cohorts. …"

Table 2_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.xlsx حسب Siriguleng Yu (14555900)

"…</p>Results<p>The treatment significantly reduced diet-induced adiposity and decreased inflammatory responses. …"

Neurodevelopmental H2AK119ub enrichment within H3K4me3-positive promoters subdues transcription. حسب Aditya Parmar (22331873)

"…<b>(J)</b> RNAseq data within genes possessing H3K4me3-only promoters that experienced a significant increase in H2AK119ub. <b>(K)</b> RNAseq data within genes possessing bivalent promoters that experienced a significant increase in H2AK119ub. …"

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study حسب Lu Wang (45927)

"…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …"

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx حسب Mehri Hajiaghayi (19822665)

"…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …"

Table 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.xlsx حسب Ying Liu (18461)

"…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …"