Data Sheet 1_Global trends and future predictions of gastrointestinal ulcers in youth.pdf by Kun He (178646)

“…</p>Conclusion<p>In 2019, the global burden of gastrointestinal ulcers showed significant increases in prevalent and incident cases, DALYs, and deaths compared to 1990. …”

Data Sheet 2_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.pdf by Juan Zhang (48597)

“…Our initial findings revealed a lower serum level of miR-216a-5p in DN patients (P < 0.05). In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Data Sheet 1_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.docx by Juan Zhang (48597)

“…Our initial findings revealed a lower serum level of miR-216a-5p in DN patients (P < 0.05). In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

Supplementary Material for: Collagen I Derived Extracellular Matrix Motifs Alter Fibroblast Regenerative Response by figshare admin karger (2628495)

“…Soluble free mECMs induced changes in fibroblast phenotype as indicated by a decrease in proliferation, decrease in nuclei area, and increase in percentage of elongated cells. …”

Data Sheet 1_Perturbations in gut microbiota composition in patients with autoimmune neurological diseases: a systematic review and meta-analysis.pdf by Xiaolin Deng (5214647)

“…Regarding α-diversity, except for Chao1, which showed a consistent small decrease (SMD = −0.26, 95% CI = −0.45 to −0.07, p < 0.01), other indices demonstrated no significant changes. …”

Data Sheet 1_Harnessing microbial allies: enhancing black alder resilience to PAH stress through microbial symbiosis.docx by Greta Striganavičiūtė (21266969)

“…In family 13-99-1K, S. yanoikuyae significantly enhanced defense mechanisms under phenanthrene exposure, evidenced by reduced malondialdehyde (MDA) levels and increased antioxidant enzyme activity. …”

<i>Piriformospora indica</i> Mediated Amelioration of Salt Stress in <i>Solanum melongena</i> L. Plants under Greenhouse- A Study on Stomatal Opening/Closure by Swetha Seshagiri (20586100)

“…<p>Salinity is a major abiotic stress that negatively affects agricultural land, significantly reducing crop yields. It alters the fundamental structure of the soil, causing a decrease in porosity, reduced aeration, and impaired water movement. …”

Supplementary information files for "Incorporating fluid-structure interactions for modelling of pyramidal hollow microneedles for transdermal drug delivery" by Rahul Nadda (19435999)

“…As expected, SS demonstrated the lowest von Mises stress (13 213 N/m2 ) while PLA and PGA exhibited a decrease in the stress level as the HMN wall thickness increased. …”

Data Sheet 1_Characterization of vaginal microbiota across female reproductive phases.zip by Qingzhi Zhai (21265412)

“…Firmicutes dominate in the early reproductive phases but decrease notably during lactation and menopause. Conversely, Bacteroidetes, Actinobacteria, and Proteobacteria increase in later phases. …”

Presentation 4_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

Presentation 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

Presentation 3_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

Table 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series ana... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

Presentation 2_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Notably, hospitalization rates in adolescent girls (12–17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02–6.85, p < 0.001), whereas the increase was not significant for boys in the same age group (level change, HRR 1.42, 95%CI 0.65–3.11, p = 0.378). …”

Image 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.pdf by Zhanyi Yang (5142182)

“…Furthermore, MORC4 knockdown led to an increased expression of genes associated with cholesterol synthesis (HMGCR), varying levels of genes implicated in the uptake of fatty acids and cholesterol (PCSK9, PLTP, CD36), and a decrease in the levels of genes involved in triglyceride hydrolysis (APOC2, APOA4, LIPG, LIPA). …”

Table 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.xlsx by Zhanyi Yang (5142182)

“…Furthermore, MORC4 knockdown led to an increased expression of genes associated with cholesterol synthesis (HMGCR), varying levels of genes implicated in the uptake of fatty acids and cholesterol (PCSK9, PLTP, CD36), and a decrease in the levels of genes involved in triglyceride hydrolysis (APOC2, APOA4, LIPG, LIPA). …”

Supplementary Material for: Does manual acupuncture improve gastro-esophageal reflux disease symptoms? A trial sequential meta-analysis by figshare admin karger (2628495)

“…Conclusion: Manual acupuncture has the potential to alleviate the severity of symptoms and decrease the recurrence rate in patients with GERD. …”

Data Sheet 1_Comparative efficacy and safety of antidiabetic agents for post-transplant diabetes mellitus: a network meta-analysis.docx by Shanbiao Hu (15063765)

“…Background<p>Post-transplant diabetes mellitus (PTDM) significantly compromises patient and graft outcomes. …”

Supplementary Material for: Effect of frail phenotype on cardiorenal risk and healthcare utilization in older patients with chronic kidney disease by Sun C.-Y. (10070377)

“…The primary composite renal outcome was a ≥ 25 % decrease in eGFR concurrent with CKD stage progression or dialysis initiation. …”

Data Sheet 1_Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications.docx by Guanglu Li (2315128)

“…</p>Conclusion<p>This study provides prioritisation evidence for memantine in migraine prevention, as memantine can significantly decrease the frequency of migraine attacks, improves response rates, and fair acceptability. …”