Data Sheet 1_Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.pdf by Tao Jiang (28401)

“…Background<p>The clinical application of recombinant tissue plasminogen activator (rt-PA) is significantly constrained by hemorrhagic transformation (HT), a common and severe complication following thrombolysis for ischemic stroke. …”

P_i‐treatment aggravates calcification and induces phenotypic transition of VSMCs. by Razia Rashid Rahil (22772495)

“…(B) Summarized bar graph showed P_i treatment significantly increased calcium deposition. Bar graphs depicted significant decrease in mRNA expression of (C) α -SMA (D) SM22α and increased (E) RUNX2 (F) OPN and (G) BMP2. …”

Data Sheet 1_Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model.pdf by Zhuo-ma Dawa (20632718)

“…After PAB treatment, the levels of CD4⁺ T lymphocytes increased and the levels of CD8⁺ T lymphocytes decreased in the host tissue surrounding the metacestodes and the spleen. …”

Data Sheet 1_Effect of administration routes on the efficacy of human umbilical cord mesenchymal stem cells in type 2 diabetic rats.pdf by Qiqiang Tao (20912420)

“…The contents of C-P and GLP-1 in serum increased significantly in all treatment groups, while the levels of INS, TNF-α, IL-6, IL-1β, IAA, and GSP decreased significantly. …”

DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx by Teng Qi (278739)

“…</p>Results<p>The findings reveal dysregulated expression of GLI1 in numerous cancers, with a significant decrease observed in BRCA. High GLI1 expression indicated better survival outcomes and was correlated with the age and stage of BRCA patients. …”

Global, regional and national burden of colorectal cancer and its risk factors, 1990-2021: a systematic analysis for the GBD 2021 by Xuan Zeng (22461799)

“…<p dir="ltr"><b>Importance: </b>Colorectal cancer (CRC) constitutes a significant segment of the global cancer burden, thereby warranting an in-depth epidemiological appraisal to inform strategic public health interventions and resource allocation. …”

Data Sheet 1_Impact of primary production and net ecosystem metabolism on carbon and nutrient cycling at the land-sea interface.docx by Louise C. V. Rewrie (21016172)

“…Despite the high nutrient concentrations and estimated GPP rates, the system was in near trophic balance, with seasonally averaged NEM estimates of -2 ± 49 mg C m^-2 d^-1 and -149 ± 41 mg C m^-2 d^-1. A significant finding is that a seasonal decrease in dissolved inorganic carbon of 125 – 160 µmol kg^-1 from May to September, and in total alkalinity of 116 – 128 µmol kg^-1 from December to August, was likely driven by the concurrent and significant seasonal uptake of inorganic carbon by primary producers in the upper estuary and upstream regions. …”

Proteomic and phosphoproteomic time course over sexual differentiation. by Melvin Bérard (7907558)

“…For phosphosites changing significantly upon starvation and differently during mating (middle line), co-variation was analyzed with protein levels in both starvation and mating samples. …”

Table 1_Effects of different dosages/frequency of Xuebijing injection (a Chinese patent) for sepsis: a network meta-analysis of randomized controlled trials.docx by Guangyan Liu (716821)

“…Regarding the enhancement of 28-day mortality, 50 Milliliter (ml)-tie in die (tid) exhibited optimal efficacy, 100 ml-tid demonstrated superior efficacy in ameliorating APACHE II scores, 50 ml-bis in die (bid) proved more effective in enhancing the activated partial thromboplastin time (APTT), while 100 ml-quaque die (qd) significantly improved C-reactive protein (CRP) levels. …”

Image 2_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.tif by Siyu Dai (8298864)

“…SCH772984 reduced phosphorylated ATF-2, ZO-1, and OCLN levels (p < 0.05 or p < 0.01), while ATF-2 overexpression rescued this decrease (p < 0.05 or p < 0.01), confirming ATF-2’s role in TJ protein upregulation via the MAPK pathway.…”

Table 1_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.docx by Siyu Dai (8298864)

“…SCH772984 reduced phosphorylated ATF-2, ZO-1, and OCLN levels (p < 0.05 or p < 0.01), while ATF-2 overexpression rescued this decrease (p < 0.05 or p < 0.01), confirming ATF-2’s role in TJ protein upregulation via the MAPK pathway.…”

Data Sheet 2_Analysis of endogenous hormones and transcriptomes involved in in vitro shoot apical dormancy during adventitious root formation in tree peony.docx by Yujie Yang (2327590)

“…The results showed that a decrease in trans-zeatin riboside (ZR) and gibberellic acid (GA₃) content induced shoot apical dormancy. …”

Image 3_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.tif by Siyu Dai (8298864)

“…SCH772984 reduced phosphorylated ATF-2, ZO-1, and OCLN levels (p < 0.05 or p < 0.01), while ATF-2 overexpression rescued this decrease (p < 0.05 or p < 0.01), confirming ATF-2’s role in TJ protein upregulation via the MAPK pathway.…”

Image 1_α-Glycerol monolaurate promotes tight junction proteins expression through PKC/MAPK/ATF-2 signaling pathway.tif by Siyu Dai (8298864)

“…SCH772984 reduced phosphorylated ATF-2, ZO-1, and OCLN levels (p < 0.05 or p < 0.01), while ATF-2 overexpression rescued this decrease (p < 0.05 or p < 0.01), confirming ATF-2’s role in TJ protein upregulation via the MAPK pathway.…”

Data Sheet 1_Analysis of endogenous hormones and transcriptomes involved in in vitro shoot apical dormancy during adventitious root formation in tree peony.xlsx by Yujie Yang (2327590)

“…The results showed that a decrease in trans-zeatin riboside (ZR) and gibberellic acid (GA₃) content induced shoot apical dormancy. …”

Image_1_Mechanical acupuncture at HT7 attenuates alcohol self-administration in rats by modulating neuroinflammation and altering mPFC-habenula-VTA circuit activity.TIF by Su Yeon Seo (4967656)

“…HT7 stimulation reversed these alterations by increasing BDNF expression in the mPFC and decreasing TH levels in the VTA (p < 0.05). …”

Image_2_Mechanical acupuncture at HT7 attenuates alcohol self-administration in rats by modulating neuroinflammation and altering mPFC-habenula-VTA circuit activity.TIF by Su Yeon Seo (4967656)

“…HT7 stimulation reversed these alterations by increasing BDNF expression in the mPFC and decreasing TH levels in the VTA (p < 0.05). …”

Supplementary Material for: Fibrillin-1 deficiency perturbs aortic cholinergic relaxation and adrenergic contraction in a mouse model of early onset progressively severe Marfan syn... by Cantalupo A. (20574239)

“…Results: Isometric force measurements of aortic rings from 16-day-old male Fbn1mgR/mgR mice revealed a significant reduction in acetylcholine (ACh)-induced relaxation and increased phenylephrine (PE)-promoted contractility, associated with abnormally low eNOSSer1177 phosphorylation, decreased NO production and augmented superoxide levels. …”

Data Sheet 1_Clinical utility of nanopore-targeted sequencing for diagnosing and treating pulmonary infectious diseases from bronchoalveolar lavage fluid.docx by Gen Li (743590)

“…Additionally, prior antibiotic exposure had no influence on the detection efficiency of NTS but significantly hindered that of CMTs. After antibiotic adjustments based on NTS findings, 87.76% of patients showed significant improvement, with a notable decrease in the level of inflammatory markers (CRP, NP, PCT, WBC) post-treatment. …”

Data Sheet 2_Clinical utility of nanopore-targeted sequencing for diagnosing and treating pulmonary infectious diseases from bronchoalveolar lavage fluid.xlsx by Gen Li (743590)

“…Additionally, prior antibiotic exposure had no influence on the detection efficiency of NTS but significantly hindered that of CMTs. After antibiotic adjustments based on NTS findings, 87.76% of patients showed significant improvement, with a notable decrease in the level of inflammatory markers (CRP, NP, PCT, WBC) post-treatment. …”