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20461
Data Sheet 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.csv
Published 2025“…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…”
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20462
Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf
Published 2025“…<p>Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor immunization responses afflict patients. …”
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20463
Data Sheet 1_Home-field advantage effect weakened over time but was strengthened by labile carbon input in later litter decomposition stage.doc
Published 2025“…Additionally, glucose additions led to a significant increase of 15.19% in the HFA effect (p<0.05) during later decomposition stage, which was primarily associated with Sordariomycetes. …”
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20464
Supplementary Material for: Phosphorus restriction prevents rapamycin-induced kidney damage in rats
Published 2024“…Results: When compared with placebo, rapamycin administration to Nx rats resulted in significant increases in IN (4.17±0.74 vs 1.51±0.53 %) and TD (14.45±1.51 vs 8.61±1.83 %). …”
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20465
Table 1_Efficacy of the early start Denver model combined with the TEACCH program in children with autism spectrum disorder.docx
Published 2025“…</p>Results<p>Both groups showed significant within-group improvement after intervention, but the combined observation group demonstrated greater gains. …”
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20466
Data Sheet 1_Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission.pdf
Published 2025“…After dietary intervention, a significant reduction in specific inflammatory and metabolic biomarkers was observed, with distinct effects depending on tumor type. …”
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20467
Dynamic visualization of DNA methylation in cell cycle genes during iPSC cardiac differentiation
Published 2024“…<p>Existing analyses with conventional assays have generated significant insights into static states of DNA methylation but were unable to visualize the dynamics of epigenetic regulation.…”
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20468
DataSheet2_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip
Published 2025“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”
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20469
DataSheet1_Vitamin D Deficiency and Associated Factors in Children: A Multicenter Study of 21,811 Samples in Southern China.docx
Published 2025“…</p>Results<p>Serum 25(OH)D levels decreased with age (p trend <0.001). VDD prevalence increased significantly from 3.7% (95% CI: 3.2, 4.3) in children aged 0–3 years to 43.5% (95% CI: 42.1, 45.0) in those aged 13–18 years. …”
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20470
<b>Relationship between </b><b>plant</b><b> </b><b>anatomical </b><b>traits and yield among </b><b>different</b><b> winter wheat genotypes in</b><b> </b><b>dry environment</b><b>s<...
Published 2025“…Our results suggests that larger root xylem area, decreased root cortical tissue with lower root respiration, higher abaxial stomatal density with smaller but more stomata in the flag leaf have contributed to increased yields in dry environments. …”
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20471
Image3_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff
Published 2024“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
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20472
Data Sheet 1_An exploratory study on the metagenomic and proteomic characterization of hypothyroidism in the first half of pregnancy and correlation with Th1/Th2 balance.docx
Published 2025“…</p>Conclusion<p>Increased P. vulgatus and B. fragilis, decreased DGKK and S10A8 proteins, and a left shift in the Th1/Th2 balance in patients with hypothyroidism in the first half of pregnancy may be associated with the development of the disease.…”
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20473
The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model
Published 2025“…Immune analysis revealed decreased numbers of resting CD4⁺ memory T cells and Tregs (<i>P</i> < 0.01), alongside expanded proinflammatory cells (M1/M2 macrophages, neutrophils; <i>P</i> < 0.01). …”
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20474
Location map of the study area.
Published 2025“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”
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20475
Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i>
Published 2024“…Expression analysis revealed significant upregulation of BbNoxs during fungal growth and infection. …”
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20476
Video 5_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4
Published 2024“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”
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20477
Table 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.docx
Published 2024“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”
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20478
Image 2_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif
Published 2025“…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …”
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20479
Different model detection results comparison.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”
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20480
Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”