Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…In this study, we examined the influence of CBS/H₂S on anxiety and depression-like behavior following the inescapable foot shock (IFS) procedure during early adolescence (postnatal days 28-35) or adulthood (postnatal days 63-70).</p>Results<p>Our results showed that adult PTSD mice exhibited more pronounced decreases in H₂S content and CBS expression in the hippocampus, which were associated with anxiety and depression-like behavior compared with adolescent PTSD mice. …”

Data Sheet 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.xlsx by Bing Gu (276393)

“…In this study, we examined the influence of CBS/H₂S on anxiety and depression-like behavior following the inescapable foot shock (IFS) procedure during early adolescence (postnatal days 28-35) or adulthood (postnatal days 63-70).</p>Results<p>Our results showed that adult PTSD mice exhibited more pronounced decreases in H₂S content and CBS expression in the hippocampus, which were associated with anxiety and depression-like behavior compared with adolescent PTSD mice. …”

Effect of COVID-19 infection on thyroid function status and clinical indexes among hypothyroid outpatients by Bingxin Li (1876975)

“…In HT group, thyroid-stimulating hormone (TSH) levels decreased significantly compared to pre-infection levels (<i>p</i> = 0.013), while free triiodothyronine (FT3) levels increased at D90 compared to both D30 post-infection and pre-infection levels (<i>p</i> < 0.001 and <i>p</i> = 0.005). …”

Table 1_Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases.docx by Maria Dodina (20223012)

“…In the preclinical research phase, in vitro models complement in vivo models by reducing animal studies, decreasing costs, and shortening research timelines. …”

Image 1_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg by Xiaohui Feng (2869535)

“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”

Image 2_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg by Xiaohui Feng (2869535)

“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”

Image 6_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Image 4_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Image 3_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Image 5_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Image 2_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Table 1_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.docx by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Image 1_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg by Fushan Lu (20413670)

“…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …”

Data Sheet 1_Elevated SerpinB2 regulates MUC5AC expression via STAT6 signaling in nasal epithelial cells in allergic rhinitis.docx by Jing Li (10611)

“…</p>Results<p>SerpinB2 expression was significantly increased in both intermittent and persistent AR compared to normal mucosa from HC. …”

<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b> by Ji-Seok Kim (21287672)

“…Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …”

<b>Does long term fertilization impact soil carbon’s functional group composition and its distribution in aggregates?</b> by Prabhsimran Singh (20789675)

“…<p dir="ltr">The carbon (C) sink capacity of soil hinges its ability to retain C over time. …”

DataSheet1_Effect of copper on nitrogen uptake, transportation, assimilation processes, and related gene expression in Chinese cabbage [Brassica campestris L. ssp. Chinensis (L.)]... by Xin Wen (470639)

“…<p>Improving vegetable yield and optimizing its quality through nutrient management have long been central to plant nutrition and horticultural science. …”

Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis by Chenyu Luo (12443535)

“…</p>…”

Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs by Gui Su (128698)

“…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …”

Supplementary Material for: Identifying novel inflammatory protein biomarkers and drug targets of inflammatory bowel disease by integrating Mendelian randomization, bioinformatics,... by Wang F. (3215361)

“…Additionally, CD was significantly associated with elevated levels of three circulating inflammatory proteins, which are suggested to be the consequences of CD. …”