Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Mononuclear cells isolated from vaginal tract, spleen, nasal associated lymphoid tissue (NALT), cervical lymph nodes (cLN) and iliac lymph nodes (iLN) tissues were analyzed by flow cytometry for plasma and memory B cell phenotypes.</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …"

Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Mononuclear cells isolated from vaginal tract, spleen, nasal associated lymphoid tissue (NALT), cervical lymph nodes (cLN) and iliac lymph nodes (iLN) tissues were analyzed by flow cytometry for plasma and memory B cell phenotypes.</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …"

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Mononuclear cells isolated from vaginal tract, spleen, nasal associated lymphoid tissue (NALT), cervical lymph nodes (cLN) and iliac lymph nodes (iLN) tissues were analyzed by flow cytometry for plasma and memory B cell phenotypes.</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …"

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Mononuclear cells isolated from vaginal tract, spleen, nasal associated lymphoid tissue (NALT), cervical lymph nodes (cLN) and iliac lymph nodes (iLN) tissues were analyzed by flow cytometry for plasma and memory B cell phenotypes.</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …"

Data of all figures حسب Bingqing Ye (5149703)

"…<p dir="ltr">Sepsis, a life-threatening organ dysfunction caused by dysregulated host responses to infection, often leads to sepsis-associated acute lung injury (SALI), a major contributor to mortality. …"

Table 1_The RNA-binding protein ProQ directly binds and regulates virulence genes in enterohemorrhagic Escherichia coli O157:H7.docx حسب Ye Qian (7400186)

"…<p>ProQ has recently emerged as a major post-transcriptional regulator in bacteria through directly binding to diverse mRNAs and small regulatory RNAs (sRNAs). …"

Raw Data from Bioassays and R Code for Statistical Analyses in Manuscript Submitted to the <i>Journal of Chemical Ecology</i> حسب Masayuki Hayashi (12339841)

"…However, when minor variations in chemical structure do not significantly impact the organisms, a generalized response to similar chemicals without discrimination might be more adaptive. …"

Table 1_Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway.docx حسب Yo Sep Hwang (17967916)

"…<p>Cancer cachexia is a complex syndrome marked by appetite loss, weakness, fatigue, significant weight loss, and depletion of both adipose and muscle tissue, driven by metabolic and inflammatory alterations caused by tumors. …"

Image 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.jpg حسب Jiajun Chen (1279269)

"…</p>Conclusion<p>The enrichment of Prevotella melaninogenica species in LRT and a decreased level of peripheral blood lymphocytes are associated with CIP/RP.…"

Data Sheet 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.zip حسب Jiajun Chen (1279269)

"…</p>Conclusion<p>The enrichment of Prevotella melaninogenica species in LRT and a decreased level of peripheral blood lymphocytes are associated with CIP/RP.…"

Data Sheet 1_Alpine steppe vegetation communities are more sensitive to plateau pika disturbance than alpine meadows.docx حسب Rui Hua (127074)

"…</p>Results<p>The results showed that the alpine steppe was more sensitive to pika disturbance, with significant decreases in biomass, vegetation height, and coverage even at low disturbance levels. …"

Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx حسب Ji Yang (114503)

"…</p>Methods<p>A murine IBD model was induced by 3% dextran sulfate sodium (DSS). …"

Data Sheet 1_Global soil moisture dynamics: attribution of contributions and their association with GPP.docx حسب Yang Li (7082)

"…<p>Soil moisture (SM) is central to the global land-atmosphere interaction and is of significant research importance. …"

Data Sheet 1_The longitudinal associations between filial piety belief and mobile phone addiction: from the perspective of self-determination theory.zip حسب Hua Wei (60877)

"…In contrast, for adolescents with high levels of ego-depletion, basic need satisfaction has no significant effect on mobile phone addiction.</p>…"

EU Data.csv<b>EU Data-1:</b> Age, sex, and medications used in patients with Parkinson’s disease.<b>EU Data-2:</b> Experimental parameters during off and on states of anti-Parkinso... حسب Eiichirou Urasaki (20502995)

"…The change in CSP latency exhibited a significant mild correlation with the change in the NRS scores (p < 0.05). …"

Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf حسب Mattia Dalle Nogare (22696022)

"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"

Data Sheet 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf حسب Mattia Dalle Nogare (22696022)

"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"

Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx حسب Mattia Dalle Nogare (22696022)

"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"

Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx حسب Mattia Dalle Nogare (22696022)

"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"

Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx حسب Mattia Dalle Nogare (22696022)

"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"