Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…Objective<p>The phase III ASTRUM-007 trial demonstrated significant clinical benefit in patients with PD-L1-positive esophageal squamous cell carcinoma (ESCC) treated with first-line serplulimab plus chemotherapy. …”

Supplementary Material for: Impact of antibiotic therapy in patients with cholangiocarcinoma treated with chemoimmunotherapy by figshare admin karger (2628495)

“…In the AT population, the incidence of cholangitis (p = 0.0017), ALT elevation (p = 0.0009), fever (p = 0.0021), decreased appetite (p = 0.0007), itching (p = 0.0081), and rash (p = 0.012) was significantly higher compared to the NAT. …”

Table 1_Multicenter epidemiology of Stenotrophomonas maltophilia bloodstream infections in Indian ICUs: building digital surveillance network.pdf by Parul Singh (191877)

“…High resistance was observed to tobramycin (92%), amikacin (80%), and piperacillin-tazobactam (70%), while trimethoprim-sulfamethoxazole (64.7–94.7%), levofloxacin (93%), and minocycline (94.1%) retained activity.</p>Conclusion<p>S. maltophilia represents a significant ICU pathogen in India, underscoring the urgent need for genomic surveillance and resistance-guided therapeutic strategies.…”

Table 2_Relationships between rumen methanogens and fungal communities and their response to changes in alfalfa forms and starch in sheep diets.xlsx by Wenliang Guo (14825407)

“…The relative abundance of Aspergillus in the AHLR diet was significantly higher than in the AS diets (P < 0.01), and the relative abundance of Occultifur and Meyerozyma were decreased in the AH diets than in the AS diets (P < 0.05). …”

Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…</p> <p>This is a prospective observational registry at 70 sites in Germany, categorising patients by PCSK9-mAb treatment status at baseline. …”

Table 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.xlsx by Yan Li (23143)

“…Sensitivity analyses verified the robustness and validity of these findings.</p>Conclusions<p>These findings provide a deeper understanding of the intricate relationships among lifestyle and metabolites and the development of age-related diseases.…”

Supplementary file 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.docx by Yan Li (23143)

“…Sensitivity analyses verified the robustness and validity of these findings.</p>Conclusions<p>These findings provide a deeper understanding of the intricate relationships among lifestyle and metabolites and the development of age-related diseases.…”

Table 1_Relationships between rumen methanogens and fungal communities and their response to changes in alfalfa forms and starch in sheep diets.docx by Wenliang Guo (14825407)

“…The relative abundance of Aspergillus in the AHLR diet was significantly higher than in the AS diets (P < 0.01), and the relative abundance of Occultifur and Meyerozyma were decreased in the AH diets than in the AS diets (P < 0.05). …”

Supplementary file 1_ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels.pdf by Xuexue Liu (3271641)

“…Mechanistically, exposure to ZnO NPs did not significantly affect the IK1, but it markedly decreased I_Na and I_Ca−L currents, resulting in a reduced amplitude and shortened duration of the action potential in cardiomyocytes. …”

Data Sheet 1_IgE autoantibodies to nuclear antigens in patients with different connective tissue diseases: re-evaluation and novel findings.docx by Kathrin Kramer (20906207)

“…IgE anti-dsDNA- but not the other IgE autoantibodies decreased under immunosuppressive therapy.</p>Conclusion<p>IgE anti-SSA/Ro-, -SSB/La-, -RNP-, and -dsDNA antibodies show a high frequency and specificity for the prevailing CTD. …”

Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png by Yu Liu (6938)

“…</p>Methods<p>Based on data from the FDA Adverse Event Reporting System (FAERS) database, a retrospective pharmacovigilance study was conducted to evaluate temozolomide-related adverse events. …”

Table 1_Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars.doc by Xiaohui Sun (520181)

“…<p>Salinity is a major abiotic stress that threatens crop yield and food supply in saline soil areas. …”

Table_2_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX by Enas Al-khlifeh (17286364)

“…We found that bioclimatic zone had a significant effect on the gut microbiota composition while host phylogeny did not. …”

Data Sheet 1_Involvement of long non-coding RNA (lncRNA) MALAT1 in shear stress regulated adipocyte differentiation.docx by Justin Caron (21249173)

“…Our findings indicate that shear stress influences adipocyte differentiation mainly through the downregulation of MALAT1, highlighting a significant interplay between biophysical cues and lncRNAs. …”

Table 1_Integrative analysis of transcriptome and metabolome reveals molecular mechanisms of dynamic change of storage substances during dehydration and drying process in peanuts (... by Jingjing Deng (468275)

“…S3d was the key period during which the content of most of the metabolites changed significantly. The contents of most amino acids(87%) and their derivatives decreased significantly, and most of the lipids(68%), sugars(67%) and flavonoids(87%) accumulated to their peak at S3d. …”

Table_1_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX by Enas Al-khlifeh (17286364)

“…We found that bioclimatic zone had a significant effect on the gut microbiota composition while host phylogeny did not. …”

Data Sheet 1_Integrative analysis of transcriptome and metabolome reveals molecular mechanisms of dynamic change of storage substances during dehydration and drying process in pean... by Jingjing Deng (468275)

“…S3d was the key period during which the content of most of the metabolites changed significantly. The contents of most amino acids(87%) and their derivatives decreased significantly, and most of the lipids(68%), sugars(67%) and flavonoids(87%) accumulated to their peak at S3d. …”

Table1_Myocardial infarction in rats was alleviated by MSCs derived from the maternal segment of the human umbilical cord.DOCX by Shuifen Sun (19855329)

“…</p>Conclusion<p>Our data demonstrated that maternal segment-derived MSCs were a superior cell source for regenerative repair after MI. …”

Data Sheet 1_Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.xlsx by Zhenzhen Wang (250368)

“…</p>Methods<p>From 2015 to 2022, a total of 3,605 strains isolated from 10 designated TB medical institutions in the main urban and county/township areas of Luoyang City, China, were confirmed as MTBC members through polymerase chain reaction (PCR) targeting a specific insertion sequence IS6110. …”

<b>Two therapeutic approaches for vancomycin-induced acute kidney injury: urinary acidification or inhibition of organic anion transporters with probenecid</b> by Thibault Le Moulec (20854373)

“…Similarly, probenecid treatment reduced plasma urea and ameliorated tubular lesions, with a significant reduction in cast formation beginning on the third day as confirmed by intravital microscopy. …”