يعرض 20,021 - 20,040 نتائج من 21,342 نتيجة بحث عن '(( significance ((set decrease) OR (a decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.57s تنقيح النتائج
  1. 20021

    Table 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.docx حسب Jing Lv (128179)

    منشور في 2025
    "…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"
  2. 20022

    The analgesic effect of total saponins of Tribulus terrestris on neuropathic pain was studied based on TLR4/NF-κB pathway حسب Wu-Xia Guo (20832169)

    منشور في 2025
    "…ELISA was employed to detect levels of IL-1β, IL-6, and TNF-ɑ in spinal cord. CCI significantly decreased PMWT and TL. …"
  3. 20023

    Image 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.tif حسب Jing Lv (128179)

    منشور في 2025
    "…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …"
  4. 20024

    Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

    منشور في 2025
    "…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"
  5. 20025

    Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx حسب Yuzhe Tan (22274731)

    منشور في 2025
    "…</p>Results<p>Multidimensional feature analysis revealed a characteristic pathological compensation pattern of “decreased cyclogram features with increased sample entropy” in the KOA group, while the TKA group demonstrated postoperative improvements in both dimensions. …"
  6. 20026

    Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx حسب Chunyu Yao (13559263)

    منشور في 2025
    "…</p>Results and discussion<p>We established three dosage groups (2.5 × 10<sup>8</sup>, 5 × 10<sup>8</sup>, and 1.5 × 10<sup>9</sup> CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …"
  7. 20027

    Image_1_Untargeted metabolomics reveals the alteration of metabolites during the stewing process of Lueyang black-bone chicken meat.pdf حسب Ling Wang (56577)

    منشور في 2024
    "…During the heating process, the abundances of Ser, Ala, Tyr, niacinamide, galactose, guanosine 3′-monophosphate and inosine 5′-monophosphate in chicken meat significantly decreased and were partially dissolved in the soup. …"
  8. 20028

    Table 1_Exploring the antiviral potential of shikimic acid against Chikungunya virus through network pharmacology, molecular docking, and in vitro experiments.docx حسب Jialiang Xin (6941207)

    منشور في 2025
    "…<p>Chikungunya virus (CHIKV) is an arbovirus that can lead to chronic arthritis and significantly diminish the quality of life of patients. …"
  9. 20029

    Image 1_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

    منشور في 2025
    "…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"
  10. 20030

    Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model حسب figshare admin karger (2628495)

    منشور في 2025
    "…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …"
  11. 20031

    Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf حسب Rong Wu (152554)

    منشور في 2025
    "…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…"
  12. 20032

    Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx حسب Feilong Yang (1472296)

    منشور في 2025
    "…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …"
  13. 20033

    Data Sheet 1_The pan-cancer landscape of aldo-keto reductase1B10 reveals that its expression is diminished in gastric cancer.docx حسب Anqi Wu (3413069)

    منشور في 2024
    "…In the stomach, along with the diminishing of AKR1B10 expression, CD68+ macrophage increased and CD19+ B cell decreased in gastric cancer.</p>Discussion<p>These data indicates that AKR1B10 may be an important factor in the development and progression and a potential therapeutic target for multiple cancers, but plays as a protector in the gastric tissues.…"
  14. 20034

    Image 3_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

    منشور في 2025
    "…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"
  15. 20035

    DataSheet1_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx حسب Hongyang Guo (9466516)

    منشور في 2024
    "…The phenotypic traits, resistance indicators, and transcriptional and metabolic regulation of MdKAI2 were identified. KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …"
  16. 20036

    DataSheet2_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx حسب Hongyang Guo (9466516)

    منشور في 2024
    "…The phenotypic traits, resistance indicators, and transcriptional and metabolic regulation of MdKAI2 were identified. KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …"
  17. 20037

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

    منشور في 2025
    "…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …"
  18. 20038

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

    منشور في 2025
    "…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …"
  19. 20039

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

    منشور في 2025
    "…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …"
  20. 20040

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries حسب Xiyin Huang (11528200)

    منشور في 2025
    "…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …"