Table 3_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.xlsx by Hongyu Zhou (352858)

“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”

Image 3_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg by Dylan Krajewski (5881880)

“…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”

Supplementary file 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”

Divergent gene expression in <i>D. sechellia.</i> by Daehan Lee (5043377)

“…<p><b>(A)</b> Histogram of the frequency of <i>D. sechellia</i>-specific DEGs across 94 cell types, arranged by decreasing DEG number. The remaining 13 cell types with no DEGs are not shown. …”

Data Sheet 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.docx by Yiwen Li (354034)

“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”

Data Sheet 1_Efficacy of different pharmaceutical forms of Curcuma longa or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and m... by Pedro de Padua G. Amatto (20981201)

“…The pooled analysis showed significant reductions in WHO scores and oral pain compared to placebo. …”

Table 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -induced... by Yanping Wang (275956)

“…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…”

Table 3_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx by Yanyao Lu (22163632)

“…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”

Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Exploring the dynamics of gut microbiota, antibiotic resistance, and chemotherapy impact in acute leukemia patients: A comprehensive metagenomic analysis by Ying Luo (381053)

“…<p>Leukemia poses significant challenges to its treatment, and understanding its complex pathogenesis is crucial. …”

Table 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.docx by Guanfei Zhao (3815596)

“…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …”

Table 1_Integrated analysis of serum metabolomics and fecal microbiome in infants with necrotizing enterocolitis.docx by Zhi-ying Lin (12997350)

“…Serum metabolomics identified significantly decreased ornithine, DL-arginine, L-threonine, leucine, and D-proline in NEC-D versus non-NEC. …”

DataSheet3_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Data Sheet 2_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.docx by Xiu Sun (8539698)

“…In the CHB-HCC, CC-HCC, and DC-HCC groups, the abundance of Bacteroides, Prevotella, and Faecalibacterium gradually decreased, whereas Klebsiella, Haemophilus, and Streptococcus increased. …”

Land Use Change Transfer Diagram. by Wanzhuang Huang (17357306)

“…The results indicated that from 1990 to 2020, the area of unused land in the Shiyang River Basin decreased the most, mainly converted into farmland, construction land, and water areas. …”

Table 6_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.xlsx by Tien Le (634791)

“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”

Data Sheet 3_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf by Ilmari Pyykkö (2855153)

“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”

Data Sheet 1_Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai.xlsx by Xingxing Yin (7919447)

“…</p>Results<p>The number of older adult care institutions in Shanghai has seen significant growth over the past 20 years, increasing fourfold due to the rise in both public and private facilities. …”

Table_2_Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during Helicobacter pylori eradication: a randomized, double-blind,... by Zhongxue Han (19855215)

“…After treatment, the GSRS score decreased significantly in the probiotic group (p = 0.039). …”

Table 1_Intra-tumor and peritumoral radiomics and deep learning based on ultrasound for differentiating fibroadenoma and phyllodes tumor: a multicenter study.docx by Guoxiu Lu (15393095)

“…This approach reduces diagnostic ambiguity in Bi-RADS 4 lesions and decreases unnecessary biopsies, demonstrating significant clinical utility for precision diagnosis of breast fibroepithelial tumors.…”