Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Data Sheet 1_Probiotic administration correlated with reduced diarrheal incidence and improved gut microbiota diversity in young goats.pdf حسب Mohamed Osman Abdalrahem Essa (21562583)

"…The predominant phyla identified were Pseudomonadota, Bacteroidetes, and Bacillota.Increased levels of Xylanibacter, UCG-055, Bacteroides, and Escherichia-Shigella were noted in healthy treated kids, while Prevotellaceae UG_001 and Proteus decreased.</p>Discussion<p>The findings highlight significant gut microbiota differences between healthy and diarrheal kids, suggesting that modifications in gut microbiota composition could alleviate diarrhea, contributing to preventive and therapeutic strategies for this condition.…"

Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …"

Table 1_Biliary microbiota in disease-free, obstructive and post-drainage biliary tracts.docx حسب Guiyuan Zhang (13994877)

"…Furthermore, the increased incidence of bacterial infections following biliary drainage poses a significant clinical concern; however, the relationship between biliary drainage and biliary flora remains poorly understood. …"

Data Sheet 1_High humidity environment increases FBG by impairing the intestinal barrier.zip حسب Yao Wang (102387)

"…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …"

Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx حسب Shengyou Song (22391068)

"…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…"

Table 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx حسب Man Zhao (314232)

"…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …"

Image 3_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... حسب Yangtian Jiao (21725018)

"…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …"

Data Sheet 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

"…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"

Table 2_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx حسب Yali Han (4676677)

"…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…"

Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls حسب Linjie Peng (12553717)

"…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …"

Enamel matrix derivative in the treatment of tooth replantation: from a biological basis to clinical application حسب Yao Lin (1622536)

"…Although the pooled outcomes suggested increased incidence of surface resorption (RR=1.19, <i>P</i>=0.730) and decreased risk of inflammation resorption (RR=0.68, <i>P</i>=0.560) among replanted teeth with resorption in the EMD-treated group, neither difference was statistically significant.…"

Table 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

The 16S rRNA sequencing raw data for the study titled Effects of high-dose glucocorticoids on gut microbiota in the treatment of Graves' ophthalmopathy حسب Xinhuan Su (21147710)

"…The short chain fatty acids (SCFAs)-producing ability in GO patients’ gut after high-dose GCs administration was significantly decreased. The 5-hydroxytryptamine (5-HT) levels significantly increased in gut of GO patients after administering high-dose GCs. …"

Image 2_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif حسب Inssaf Berkiks (15350248)

"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"

Table 1_Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework.docx حسب Rajamohanan Pillai Ranith (22589207)

"…</p>Results<p>Results indicated a significant increase in built-up area (~12 Km2) near high-impact sites (Devipattinam, Thondi), versus ~4 Km2 increase at low-impact sites (Pamban and Mandapam North). …"

Table 1_Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.docx حسب Mamatha K (19843110)

"…</p>Results<p>CQAB supplementation demonstrated a significant (P < 0.05) improvement in Total Nasal Symptom Score (TNSS) compared to placebo and CGM. …"

Table 4_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.xlsx حسب Guojie Ji (21518650)

"…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …"

Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx حسب Mattia Dalle Nogare (22696022)

"…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …"